Relation of Systemic Blood Pressure to Sudden Cardiac Death

The role of systolic blood pressure (SBP) as an independent risk factor for sudden cardiac death (SCD) is not well defined in a general population. Thus, we assessed the association between BP at rest and risk of SCD. BP and other risk factors were measured in a representative population-based sampl...

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Bibliographic Details
Published in:The American journal of cardiology 2012-08, Vol.110 (3), p.378-382
Main Authors: Laukkanen, Jari Antero, MD, PhD, Jennings, J. Richard, PhD, Kauhanen, Jussi, MD, PhD, Mäkikallio, Timo Heikki, MD, PhD, Ronkainen, Kimmo, MSc, Kurl, Sudhir, MD
Format: Article
Language:English
Subjects:
Adult
Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
Biological and medical sciences
Blood Pressure
Cardiology
Cardiology. Vascular system
Cardiovascular
Confidence intervals
Death, Sudden, Cardiac - epidemiology
Death, Sudden, Cardiac - etiology
Emergency and intensive care: neonates and children. Prematurity. Sudden death
Heart attacks
Humans
Hypertension - complications
Intensive care medicine
Male
Medical sciences
Mens health
Middle Aged
Prospective Studies
Risk Factors
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Summary:The role of systolic blood pressure (SBP) as an independent risk factor for sudden cardiac death (SCD) is not well defined in a general population. Thus, we assessed the association between BP at rest and risk of SCD. BP and other risk factors were measured in a representative population-based sample of 2,666 Finnish men (42 to 61 years of age). During an average follow-up period of 18.9 years (interquartile range 17.9 to 22.6), 213 SCDs occurred. Each increment 10-mm Hg of SBP at rest was associated with an increased risk of SCD (relative hazard 1.15, 95% confidence interval 1.07 to 1.25, p 145 mm Hg had a 2.04-fold (95% confidence interval 1.23 to 2.52, p = 0.003) adjusted risk for SCD compared to those with SBP
ISSN:0002-9149
1879-1913
DOI:10.1016/j.amjcard.2012.03.035