Cell Reorganization in Gastric Transplant during Esophagoplasty

We studied peculiarities of cell reorganization of the gastric transplant during the delayed period after esophagoplasty for benign pathologies of the esophagus. Polymorphism of adaptive and pathological structural rearrangements in the mucosa of the gastric tube was observed. Degenerative and atrop...

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Bibliographic Details
Published in:Bulletin of experimental biology and medicine 2011-11, Vol.152 (1), p.159-164
Main Authors: Nepomnyashchikh, L. M., Lapii, G. A., Sudovykh, I. E., Chikinev, Yu. V.
Format: Article
Language:English
Subjects:
Adult
Biomedical and Life Sciences
Biomedicine
Cell Biology
Esophagoplasty
Female
Gastric Mucosa - ultrastructure
Humans
Internal Medicine
Laboratory Medicine
Male
Middle Aged
Pathology
Stomach - cytology
Stomach - transplantation
Translated from Kletochnye Tekhnologii v Biologii i Meditsine (Cell Technologies in Biology and Medicine)
Young Adult
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Summary:We studied peculiarities of cell reorganization of the gastric transplant during the delayed period after esophagoplasty for benign pathologies of the esophagus. Polymorphism of adaptive and pathological structural rearrangements in the mucosa of the gastric tube was observed. Degenerative and atrophic changes in epithelial structures, hypertrophy of smooth muscular components, and sclerotic reorganization of the stroma were predominating morphological phenomena. Heterogeneity of ultrastructural modifications of the epithelium reflcted high secretory activity of foveal mucocytes in combination with degenerative changes in cytoplasmic organelles and impaired secretory function of fundic gland cells. Hypertrophied cells with minor ultrastructural changes, leiomyocytes with signs of biosynthesis, and degenerated smooth muscle fibers were revealed in the population of smooth muscle cells.
ISSN:0007-4888
1573-8221
DOI:10.1007/s10517-011-1477-7