Facultative Sterol Uptake in an Ergosterol-Deficient Clinical Isolate of Candida glabrata Harboring a Missense Mutation in ERG11 and Exhibiting Cross-Resistance to Azoles and Amphotericin B

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Published in:Antimicrobial Agents and Chemotherapy 2012-08, Vol.56 (8), p.4223-4232
Main Authors: HULL, Claire M, PARKER, Josie E, BADER, Oliver, WEIG, Michael, GROSS, Uwe, WARRILOW, Andrew G. S, KELLY, Diane E, KELLY, Steven L
Format: Article
Language:English
Subjects:
Amphotericin B
Amphotericin B - pharmacology
Antibiotics. Antiinfectious agents. Antiparasitic agents
Antifungal Agents
Antifungal Agents - pharmacology
Azoles
Azoles - pharmacology
Base Sequence
Biological and medical sciences
Biological Transport
Candida glabrata
Candida glabrata - drug effects
Candida glabrata - genetics
Candida glabrata - isolation & purification
Candida glabrata - metabolism
Drug Resistance, Multiple, Fungal
Drug Resistance, Multiple, Fungal - genetics
Ergosterol - metabolism
Fluconazole - pharmacology
Fungal Proteins - genetics
Humans
Mechanisms of Resistance
Medical sciences
Microbial Sensitivity Tests
Mutation, Missense
Pharmacology. Drug treatments
Pyrimidines - pharmacology
Saccharomyces cerevisiae - metabolism
Sequence Analysis, DNA
Sterol 14-Demethylase
Sterol 14-Demethylase - genetics
Sterols - metabolism
Triazoles - pharmacology
Voriconazole
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Summary:Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon Twitter current issue AAC About AAC Subscribers Authors Reviewers Advertisers Inquiries from the Press Permissions & Commercial Reprints ASM Journals Public Access Policy AAC RSS Feeds 1752 N Street N.W. • Washington DC 20036 202.737.3600 • 202.942.9355 fax • journals@asmusa.org Print ISSN: 0066-4804 Online ISSN: 1098-6596 Copyright © 2014 by the American Society for Microbiology.   For an alternate route to AAC .asm.org, visit: AAC       
ISSN:0066-4804
1098-6596
DOI:10.1128/AAC.06253-11