Cavitation of Deep Lacunar Infarcts in Patients With First-Ever Lacunar Stroke A 2-Year Follow-Up Study With MR

Studies in patients with lacunar stroke often assess the number of lacunes. However, data on how many symptomatic lacunar infarcts cavitate into a lacune are limited. We assessed the evolution of symptomatic lacunar infarcts over 2-year follow-up. In 82 patients with first-ever lacunar stroke with a...

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Bibliographic Details
Published in:Stroke (1970) 2012-08, Vol.43 (8), p.2245-2247
Main Authors: LOOS, Caroline M. J, STAALS, Julie, WARDLAW, Joanna M, VAN OOSTENBRUGGE, Robert J
Format: Article
Language:English
Subjects:
Aged
Basal Ganglia - pathology
Biological and medical sciences
Brain - pathology
Diffusion Magnetic Resonance Imaging
Female
Follow-Up Studies
Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy
Humans
Image Processing, Computer-Assisted
Internal Capsule - pathology
Magnetic Resonance Imaging
Male
Medical sciences
Middle Aged
Nervous system (semeiology, syndromes)
Neurology
Pons - pathology
Risk Factors
Stroke, Lacunar - pathology
Tomography, X-Ray Computed
Vascular Diseases - complications
Vascular diseases and vascular malformations of the nervous system
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Summary:Studies in patients with lacunar stroke often assess the number of lacunes. However, data on how many symptomatic lacunar infarcts cavitate into a lacune are limited. We assessed the evolution of symptomatic lacunar infarcts over 2-year follow-up. In 82 patients with first-ever lacunar stroke with a lacunar infarct in the deep brain regions (excluding the centrum semiovale), we performed a brain MR at presentation and 2 years later. We classified cavitation of lacunar infarcts at baseline and on follow-up MR as absent, incomplete, or complete. We recorded time to imaging, infarct size, and vascular risk factors. On baseline MR, 38 (46%) index infarcts showed complete or incomplete cavitation. Median time to imaging was 8 (0-73) days in noncavitated and 63 (1-184) days in cavitated lesions (P
ISSN:0039-2499
1524-4628
DOI:10.1161/STROKEAHA.112.660076