Influence of the neurological level of spinal cord injury on cardiovascular outcomes in humans: a meta-analysis

Background: Although motor and sensory deficits following spinal cord injury (SCI) are well known, there are still contrasting reports on how SCI affects baseline cardiovascular (CV) parameters and other autonomic functions. Study design: Meta-analysis is performed. Objectives: To examine the effect...

Full description

Saved in:
Bibliographic Details
Published in:Spinal cord 2012-07, Vol.50 (7), p.484-492
Main Authors: West, C R, Mills, P, Krassioukov, A V
Format: Article
Language:English
Subjects:
631/378
631/378/1687/1825
631/443/592
Anatomy
Antibodies
Autonomic nervous system
Biological and medical sciences
Biomedical and Life Sciences
Biomedicine
Blood pressure
Cardiovascular Diseases - diagnosis
Cardiovascular Diseases - epidemiology
Cerebrospinal fluid. Meninges. Spinal cord
Comorbidity
Heart rate
Human Physiology
Humans
Injuries of the nervous system and the skull. Diseases due to physical agents
Medical sciences
Nervous system (semeiology, syndromes)
Neurochemistry
Neurology
Neuropsychology
Neurosciences
Patient Positioning - statistics & numerical data
Prevalence
Reproducibility of Results
review
Reviews
Risk Factors
Sensitivity and Specificity
Spinal Cord Injuries - diagnosis
Spinal Cord Injuries - epidemiology
Spinal cord injury
Trauma Severity Indices
Traumas. Diseases due to physical agents
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Background: Although motor and sensory deficits following spinal cord injury (SCI) are well known, there are still contrasting reports on how SCI affects baseline cardiovascular (CV) parameters and other autonomic functions. Study design: Meta-analysis is performed. Objectives: To examine the effect of injury level on supine and seated CV function in individuals with SCI. Methods: A total of 98 studies representing 1968 individuals were retrieved for analysis. Systolic blood pressure (SBP), diastolic blood pressure (DBP) and heart rate (HR) were abstracted from the studies and compared between four groups according to the neurological lesion level, cervical (C) SCI (C4-C8), high-thoracic (HT) SCI (T1-T6), low-thoracic lumbar (LTL) SCI (below T6) and able-bodied (AB) controls. Results: In the supine position, SBP, DBP and HR were lower in C compared with HT, LTL and AB (all P
ISSN:1362-4393
1476-5624
DOI:10.1038/sc.2012.17