Myocarditis in a pediatric case of pandemic 2009H1N1 influenza

We report a 6‐year‐old boy with no major disease history or allergic conditions initially presented with pneumonia, progressed to acute respiratory distress syndrome and acute myocarditis caused by pandemic 2009H1N1 influenza diagnosed with RT‐PCR testing, successfully managed with mechanical ventil...

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Bibliographic Details
Published in:Pediatrics international 2012-08, Vol.54 (4), p.558-562
Main Authors: Jibiki, Toshiaki, Sakamoto, Ryota, Nakaya, Mitsuru, Kanazawa, Masaki, Gotoh, Fumihiro, Yamaguchi, Seiichi, Kutsuna, Satoru, Hashimoto, Yuji, Anzai, Satoshi, Abe, Katsuaki
Format: Article
Language:English
Subjects:
acute respiratory distress syndrome
Allergies
bronchial asthma
Child
Humans
Influenza
Influenza A Virus, H1N1 Subtype
Influenza, Human - epidemiology
Male
myocarditis
Myocarditis - virology
pandemic 2009 influenza A (H1N1)
Pandemics
Pediatrics
percutaneous cardiopulmonary support system
Pneumonia
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Summary:We report a 6‐year‐old boy with no major disease history or allergic conditions initially presented with pneumonia, progressed to acute respiratory distress syndrome and acute myocarditis caused by pandemic 2009H1N1 influenza diagnosed with RT‐PCR testing, successfully managed with mechanical ventilation and percutaneous cardiopulmonary support system. Marked transient elevation of IgE in acute phase of the disease and the subsequent diagnosis of atopic asthma in our patient suggested a possible role of an underlying allergic condition in the clinicopathological process. Critically ill 2009H1N1‐infected patient with acute respiratory failure should carefully be physiologically monitored together with serial assessment of biomarkers aiming at a favorable cardiac outcome by giving the timely diagnosis and intervention.
ISSN:1328-8067
1442-200X
DOI:10.1111/j.1442-200X.2012.03592.x