Statistical power for commutability testing in the presence of random, sample-related effects by use of the EP14 protocol

► Power calculations for the EP14 protocol taking sample-related effects into account. ► Effect of number of samples, replicates and virtual pooling of samples on power. ► n>40 and virtual pooling may be beneficial for uncovering matrix effects.

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Bibliographic Details
Published in:Clinica chimica acta 2012-10, Vol.413 (19-20), p.1710-1711
Main Authors: Røraas, Thomas H., Van Houcke, Sofie K., Stöckl, Dietmar, Thienpont, Linda M.
Format: Article
Language:English
Subjects:
Humans
Lack of fit error
Linear Models
Matrix effects
Practice Guidelines as Topic
Prediction interval
Quality Control
Research Design - standards
Research Design - statistics & numerical data
Sample Size
Virtual sample pooling
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Description
Summary:► Power calculations for the EP14 protocol taking sample-related effects into account. ► Effect of number of samples, replicates and virtual pooling of samples on power. ► n>40 and virtual pooling may be beneficial for uncovering matrix effects.
ISSN:0009-8981
1873-3492
DOI:10.1016/j.cca.2012.05.002