Clinical Features, Management, and Prognosis of Spontaneous Coronary Artery Dissection

Spontaneous coronary artery dissection (SCAD) is an acute coronary event of uncertain origin. Clinical features and prognosis remain insufficiently characterized. A retrospective single-center cohort study identified 87 patients with angiographically confirmed SCAD. Incidence, clinical characteristi...

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Bibliographic Details
Published in:Circulation (New York, N.Y.) N.Y.), 2012-07, Vol.126 (5), p.579-588
Main Authors: TWEET, Marysia S, HAYES, Sharonne N, GULATI, Rajiv, PITTA, Sridevi R, SIMARI, Robert D, LERMAN, Amir, LENNON, Ryan J, GERSH, Bernard J, KHAMBATTA, Sherezade, BEST, Patricia J. M, RIHAL, Charanjit S
Format: Article
Language:English
Subjects:
Adult
Aneurysm, Ruptured - complications
Aneurysm, Ruptured - diagnostic imaging
Aneurysm, Ruptured - therapy
Angioplasty, Balloon, Coronary
Biological and medical sciences
Blood and lymphatic vessels
Cardiology. Vascular system
Cohort Studies
Coronary Aneurysm - complications
Coronary Aneurysm - diagnostic imaging
Coronary Aneurysm - therapy
Coronary Angiography
Coronary Artery Bypass
Coronary heart disease
Disease Management
Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous
Electrocardiography
Female
Heart
Humans
Kaplan-Meier Estimate
Male
Medical sciences
Middle Aged
Myocardial Infarction - etiology
Myocardial Infarction - physiopathology
Prognosis
Recurrence
Retrospective Studies
Rupture, Spontaneous
Sex Factors
Treatment Outcome
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Summary:Spontaneous coronary artery dissection (SCAD) is an acute coronary event of uncertain origin. Clinical features and prognosis remain insufficiently characterized. A retrospective single-center cohort study identified 87 patients with angiographically confirmed SCAD. Incidence, clinical characteristics, treatment modalities, in-hospital outcomes, and long-term risk of SCAD recurrence or major adverse cardiac events were evaluated. Mean age was 42.6 years; 82% were female. Extreme exertion at SCAD onset was more frequent in men (7 of 16 versus 2 of 71; P
ISSN:0009-7322
1524-4539
DOI:10.1161/circulationaha.112.105718