AA amyloidosis with cutaneous manifestations. Report of one case

Systemic amyloidosis is a rare disease that can affect any organ. Its clinical manifestations are varied and nonspecific. The skin involvement of this disease is common and can be easily recognized on physical examination. We report a 57-year-old male presenting with a two years history of malaise,...

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Bibliographic Details
Published in:Revista medíca de Chile 2012-04, Vol.140 (4), p.499-502
Main Authors: Fich S, Félix, Chahuán Y, Marco, Farías N, Ma Magdalena, Cárdenas D, Consuelo, Abarzúa A, Alvaro, Araya C, Gabriela, González B, Sergio
Format: Article
Language:Spanish
Subjects:
Amyloidosis - pathology
Biopsy
Humans
Male
Middle Aged
Skin Diseases - pathology
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Summary:Systemic amyloidosis is a rare disease that can affect any organ. Its clinical manifestations are varied and nonspecific. The skin involvement of this disease is common and can be easily recognized on physical examination. We report a 57-year-old male presenting with a two years history of malaise, dyspnea and myalgias. On physical examination, ungueal dystrophy, orange pigmentation of eyelids with periocular petechiae and mild macroglossia were observed. Incisional biopsies of the eyelids, cheeks and hands were obtained. The pathological study demonstrated amyloid deposits. Since protein electrophoresis was normal, the diagnosis of AA amyloidosis was postulated.
ISSN:0717-6163
DOI:10.4067/S0034-98872012000400011