Dosimetric study of the different techniques to deal with respiratory motion for lung stereotactic radiotherapy

To evaluate the different respiratory movement management techniques during irradiation of lung tumours. Seven patients with one or more primary or secondary lung lesions less than 5 cm (11 tumours in total) had three computed tomographies (CT): free-breathing, deep-inspiration breath-hold using a s...

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Bibliographic Details
Published in:Cancer radiothérapie 2012-07, Vol.16 (4), p.263-271
Main Authors: Paumier, A, Crespeau, A, Krhili, S, Georgin-Mège, M, Tuchais, C, Mesgouez, J, Cellier, P, Lisbona, A, Denis, F, Autret, D
Format: Article
Language:eng ; fre
Subjects:
Adult
Aged
Aged, 80 and over
Female
Humans
Lung Neoplasms - radiotherapy
Male
Middle Aged
Radiotherapy - methods
Radiotherapy Dosage
Respiratory-Gated Imaging Techniques
Stereotaxic Techniques
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Summary:To evaluate the different respiratory movement management techniques during irradiation of lung tumours. Seven patients with one or more primary or secondary lung lesions less than 5 cm (11 tumours in total) had three computed tomographies (CT): free-breathing, deep-inspiration breath-hold using a spirometer, and 4-dimensional (4D). From these three acquisitions, five treatment plans were performed: free-breathing (reference method), deep-inspiration breath-hold, and three from the 4D CT: two breathing synchronized treatments (inspiration and expiration) and one treatment taking into account all the tumour motions (definition of the internal target volume [ITV]). Planning target volume (PTV) size and dose delivered to the lungs were compared. Mean PTV with the free-breathing modality was 83 ± 28 cm(3), which was significantly greater than any of the other techniques (P
ISSN:1769-6658
DOI:10.1016/j.canrad.2012.03.004