Assembly, Fluorescence Properties and Antitumor Activity of Novel Silver(I) Cyanide Supramolecular Coordination Polymer Based on Trans-1,2-bis(4-pyridyl)ethene and Me3SnCl

• Published in: Journal of inorganic and organometallic polymers and materials 2012-03, Vol.22 (2), p.478-491
• Main Authors: Etaiw, Safaa El-din H., Badr El-din, Ahmed S.
• Format: Article
• Language: English
• Subjects: Chemistry; Chemistry and Materials Science; Inorganic Chemistry; Organic Chemistry; Polymer Sciences
• ISSN: 1574-1443; 1574-1451
• DOI: 10.1007/s10904-011-9602-7

A bimetallic supramolecular coordination polymer; {[(Me 3 Sn) 8 Ag 4 (OH) 4 (CN) 8 (tbpe)](tbpe)} n , 1 , was obtained by the reaction in situ of K 2 [Ag(CN) 2 ] with Me 3 SnCl and trans -1,2-bis(4-pyridyl)ethene (tbpe) in a H 2 O/MeCN/NH 3 solvent. The structure of 1 consists of discrete puckered tetranuclear chains comprising {[(Me 3 Sn) 4 Ag 2 (OH) 2 (CN) 4 ] 2 (tbpe)} in addition to one template free tbpe ligand. In these chains, the bridging hydroxyl group and the bipodal tbpe ligand are used to give two novel spacers based on the organometallic Me 3 Sn unit; i.e., a longer spacer [–CN–(Me 3 )Sn–O(H)–(Me 3 )Sn–L–(Me 3 )Sn–O(H)–(Me 3 )Sn–NC–] with a separation distance of 31.29 Å, and a relatively shorter spacer [–CN–(Me 3 )Sn–O(H)–(Me 3 )Sn–NC–] with a separation distance of 14.431 Å. Supramolecular interactions such as hydrogen bonding, π–π stacking, cation···π interactions, play a prominent role in the assembly of this compound. The structure of the SCP was also investigated by FTIR and electronic absorption spectra and thermal analysis and the data are compared to the prototype compounds. The SCP 1 exhibits strong fluorescence in acetonitrile and shows specific in vitro antitumor activity against human breast cancer cell line, MCF7.