Evaluation of select neurophysiological, clinical and psychological tests for burning mouth syndrome

• Published in: Oral surgery, oral medicine, oral pathology and oral radiology oral medicine, oral pathology and oral radiology, 2012-09, Vol.114 (3), p.325-332
• Main Authors: Mendak-Ziółko, Magdalena, PhD, DDS, Konopka, Tomasz, PhD, DDS, Bogucki, Zdzisław Artur, PhD, DDS
• Format: Article
• Language: English
• Subjects: Adult; Aged; Aged, 80 and over; Anxiety - psychology; Attitude to Health; Biological and medical sciences; Blinking - physiology; Burning Mouth Syndrome - diagnosis; Burning Mouth Syndrome - psychology; Dentistry; Electrocardiography; Electrodiagnosis - methods; Evoked Potentials, Auditory, Brain Stem - physiology; Evoked Potentials, Somatosensory - physiology; Female; Galvanic Skin Response - physiology; Heart Rate - physiology; Humans; Male; Medical sciences; Middle Aged; Neurologic Examination; Otorhinolaryngology. Stomatology; Personality Inventory; Polypharmacy; Primary Dysautonomias - diagnosis; Psychological Tests; Reaction Time - physiology; Respiration; Risk Factors; Saliva - secretion; Smoking; Surgery; Trigeminal Nerve - physiopathology
• ISSN: 2212-4403; 2212-4411
• DOI: 10.1016/j.oooo.2012.04.004

Objective The objective of this study was to identify, among an array of potential risk factors for burning mouth syndrome (BMS), those that are potentially the most significant in the development of the disease. Study Design Sixty-three participants, divided into group I (with BMS: 33 patients ages 41 to 82 years [mean age: 61.5 ± 9.4]) and group II (without BMS: 30 healthy volunteers ages 42-83 years [mean age: 60.5 ± 10.5]) were studied. All underwent a dental examination and psychological tests. Neurological tests (neurophysiological test, electroneurography, and tests of the autonomic nervous system) were performed. Mean parameters were analyzed by Student t test, Kruskal-Wallis test, and χ2 test, and multifactor analysis was performed with logistic regression and by calculating the odds ratio. Results In the logistic regression test, 3 factors were significant in the etiopathogenesis of BMS: a value more than 39 μV for the amplitude of the positive peak of the potential induced by stimulating the trigeminal nerve on the left side (P2-L); a value above 5.96 ms for the latency of wave V of the brainstem auditory evoked potentials on the right side (V–R); and a value over 2.35 ms for the latency of the sensory ulnar nerve response. Conclusions The BMS sufferer was characterized as having mild sensory and autonomic small fiber neuropathy with concomitant central disorders.