Analysis of hepatitis B surface antibody titers in B cell lymphoma patients after rituximab therapy

Hepatitis B virus (HBV) reactivation is a well-known complication after rituximab therapy in patients with B cell lymphoma. Traditionally, hepatitis B surface antibody (anti-HBs) is a protective antibody, but the effect of rituximab on these antibodies has not been well studied. In 29 B cell lymphom...

Full description

Saved in:
Bibliographic Details
Published in:Annals of hematology 2012-07, Vol.91 (7), p.1007-1012
Main Authors: Pei, Sung-Nan, Ma, Ming-Chun, Wang, Ming-Chung, Kuo, Ching-Yuan, Rau, Kun-Min, Su, Cheng-Yu, Chen, Chien-Hung
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Antibodies, Monoclonal, Murine-Derived - administration & dosage
Antibodies, Monoclonal, Murine-Derived - adverse effects
Antibodies, Monoclonal, Murine-Derived - therapeutic use
Antineoplastic Agents - administration & dosage
Antineoplastic Agents - adverse effects
Antineoplastic Agents - therapeutic use
Antineoplastic Combined Chemotherapy Protocols - administration & dosage
Antineoplastic Combined Chemotherapy Protocols - adverse effects
B-cell lymphoma
Cyclophosphamide - administration & dosage
Cyclophosphamide - adverse effects
Doxorubicin - administration & dosage
Doxorubicin - adverse effects
Female
Hematology
Hepatitis B
Hepatitis B Antibodies - analysis
Hepatitis B Antibodies - blood
Hepatitis B surface antigen
Hepatitis B Surface Antigens - immunology
Hepatitis B virus
Humans
Immunoglobulin G
Lymphoma, B-Cell - blood
Lymphoma, B-Cell - drug therapy
Lymphoma, B-Cell - immunology
Lymphoma, B-Cell - virology
Male
Medicine & Public Health
Middle Aged
Oncology
Original Article
Prednisone - administration & dosage
Prednisone - adverse effects
Regression analysis
Retrospective Studies
Rituximab
Serologic Tests
Serology
Titrimetry - methods
Vidarabine - administration & dosage
Vidarabine - adverse effects
Vidarabine - analogs & derivatives
Vincristine - administration & dosage
Vincristine - adverse effects
Virus Activation - drug effects
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Hepatitis B virus (HBV) reactivation is a well-known complication after rituximab therapy in patients with B cell lymphoma. Traditionally, hepatitis B surface antibody (anti-HBs) is a protective antibody, but the effect of rituximab on these antibodies has not been well studied. In 29 B cell lymphoma patients who were positive for anti-HBs before rituximab therapy, anti-HBs serologies before and after rituximab therapy were compared. Anti-HBs titers after rituximab treatment were significantly lower ( P  
ISSN:0939-5555
1432-0584
DOI:10.1007/s00277-012-1405-6