Anatomy, mechanics, and pathophysiology of the mitral annulus

The mitral annulus plays an important role in leaflet coaptation, in unloading mitral valve closing forces, and in promoting left atrial and left ventricular filling and emptying. Perturbations of annular mechanics figure prominently in a number of disorders including functional and ischemic mitral...

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Bibliographic Details
Published in:The American heart journal 2012-08, Vol.164 (2), p.163-176
Main Author: Silbiger, Jeffrey J., MD
Format: Article
Language:English
Subjects:
Aneurysms
Angina pectoris
Atrial Fibrillation - physiopathology
Biological and medical sciences
Biomechanical Phenomena
Calcinosis - physiopathology
Cardiology
Cardiology. Vascular system
Cardiovascular
Coronary vessels
Heart Aneurysm
Heart Valve Diseases - physiopathology
Humans
Medical sciences
Mitral Valve - anatomy & histology
Mitral Valve - physiology
Mitral Valve - physiopathology
Mitral Valve Insufficiency - physiopathology
Mitral Valve Prolapse - physiopathology
Veins & arteries
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Summary:The mitral annulus plays an important role in leaflet coaptation, in unloading mitral valve closing forces, and in promoting left atrial and left ventricular filling and emptying. Perturbations of annular mechanics figure prominently in a number of disorders including functional and ischemic mitral regurgitation, mitral valve prolapse, atrial fibrillation, mitral annular calcification, and annular submitral aneurysm. This review discusses the role of annular dysfunction in the pathogenesis of these disorders.
ISSN:0002-8703
1097-6744
DOI:10.1016/j.ahj.2012.05.014