Novel Anticaries and Remineralizing Agents: Prospects for the Future

Although the use of fluorides has been successful in reducing dental caries, the need remains to develop and evaluate new approaches and promising products for caries prevention. Comprehensive caries-prevention protocols should encompass fluoride and other agents affecting the de-/remineralization b...

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Bibliographic Details
Published in:Journal of dental research 2012-09, Vol.91 (9), p.813-815
Main Author: ten Cate, J.M.
Format: Article
Language:English
Subjects:
Anti-Bacterial Agents
Cariostatic Agents
Dental Caries - diagnosis
Dental Caries - prevention & control
Dentistry
Early Diagnosis
Humans
Probiotics
Research Design
Risk Assessment
Sugar Alcohols
Tooth Remineralization - methods
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Summary:Although the use of fluorides has been successful in reducing dental caries, the need remains to develop and evaluate new approaches and promising products for caries prevention. Comprehensive caries-prevention protocols should encompass fluoride and other agents affecting the de-/remineralization balance but also antimicrobial strategies. Different from the traditional restorative approach, the current opinion is that caries should be detected and monitored in its earliest stages, when a nonsurgical reversal can still be achieved. This paradigm shift has implications for methods of caries diagnosis, the choice of preventative materials and the design of randomized clinical trials. This article summarizes the highlights of a special conference dedicated to the topic of novel anticaries and remineralizing agents (ICNARA 2), and identifies the current consensus and remaining questions on pivotal issues in this field.
ISSN:0022-0345
1544-0591
DOI:10.1177/0022034512455032