Delayed-onset focal dystonia of the leg secondary to traumatic brain injury

Abstract A 42-year-old man presented with action-induced, stereotyped posturing of the left leg with task specificity following major traumatic brain injury less than a year earlier. Although adult onset primary leg dystonia is a recognised entity, our patient is unusual in that dystonia was an isol...

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Bibliographic Details
Published in:Journal of clinical neuroscience 2012-06, Vol.19 (6), p.916-917
Main Authors: Kemp, S, Kim, S.D.H, Cordato, D.J, Fung, V.S.C
Format: Article
Language:English
Subjects:
Adult
Anti-Dyskinesia Agents - therapeutic use
Basal ganglia
Botulinum toxin
Botulinum toxin therapy
Botulinum Toxins - therapeutic use
Brain - pathology
Brain Injuries - complications
Delayed-onset dystonia
Dystonia
Dystonia - drug therapy
Dystonia - etiology
Focal dystonia
Gliosis
Humans
Leg
Lower Extremity - physiopathology
Lower limb dystonia
Magnetic Resonance Imaging
Male
Nervous system
Neurology
Paresis
spasticity
Substantia alba
Thalamus
Traumatic brain injury
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Summary:Abstract A 42-year-old man presented with action-induced, stereotyped posturing of the left leg with task specificity following major traumatic brain injury less than a year earlier. Although adult onset primary leg dystonia is a recognised entity, our patient is unusual in that dystonia was an isolated abnormality without associated spasticity, was not preceded by ipsilateral hemiparesis and remained focal without progression to involve other body regions. MRI brain showed a small area of gliosis in the left frontal subcortical white matter but with no lesions in the basal ganglia or thalamus. The dystonia in our patient almost completely resolved with botulinum toxin therapy.
ISSN:0967-5868
1532-2653
DOI:10.1016/j.jocn.2011.08.025