Cycling exercise-induced myofiber transitions in skeletal muscle depend on basal fiber type distribution

The link between specific changes in myofiber type proportions and modulation of training in human skeletal muscle has yet to be unraveled. We investigated whether a defined increase in training volume induces a corresponding change of myofiber shifting in human skeletal muscle with distinct basal m...

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Bibliographic Details
Published in:European journal of applied physiology 2012-07, Vol.112 (7), p.2393-2402
Main Authors: Gehlert, Sebastian, Weber, Sebastian, Weidmann, Bente, Gutsche, Katrin, Platen, Petra, Graf, Christine, Kappes-Horn, Karin, Bloch, Wilhelm
Format: Article
Language:English
Subjects:
Adaptation, Physiological - physiology
Adult
Bicycling
Bicycling - physiology
Biological and medical sciences
Biomedical and Life Sciences
Biomedicine
Exercise
Exercise - physiology
Fundamental and applied biological sciences. Psychology
Genotype & phenotype
Human Physiology
Humans
Kinases
Male
Metabolism
Muscle contraction
Muscle Fibers, Skeletal - classification
Muscle Fibers, Skeletal - cytology
Muscle Fibers, Skeletal - physiology
Muscles (contractions)
Muscles (size)
Muscles (type)
Musculoskeletal system
Occupational Medicine/Industrial Medicine
Original Article
Physical fitness
Physical Fitness - physiology
Power
Recruitment
Sports Medicine
Thigh - physiology
Vertebrates: body movement. Posture. Locomotion. Flight. Swimming. Physical exercise. Rest. Sports
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Summary:The link between specific changes in myofiber type proportions and modulation of training in human skeletal muscle has yet to be unraveled. We investigated whether a defined increase in training volume induces a corresponding change of myofiber shifting in human skeletal muscle with distinct basal myofiber distribution. Twenty-one male cyclists (Age 26 ± 4 years) with different performance levels were exposed to increased cycling training volume with reduced power output for 3 months. Biopsies were taken from vastus lateralis muscle PRE–POST and the proportions of type I, IIa, IIx and IIc myofibers were determined. Total training time did not correlate to the degree of fiber type shifting of any type. In the entire sample of subjects, the proportion of type I myofibers tended to increase ( P  = 0.14) while IIa fibers decreased significantly ( P  
ISSN:1439-6319
1439-6327
DOI:10.1007/s00421-011-2209-4