Improvement in the High-Fat Diet-Induced Dyslipidemia and Adiponectin Levels by Fish Oil Feeding Combined with Food Restriction in Obese KKAy Mice

The effect on weight reduction of fish oil combined with food restriction in comparison with that of beef tallow was investigated in high-fat diet-induced obese KKAy mice. Although the reduction of body and white adipose tissue weight was similar in the two groups, fish oil increased adiponectin lev...

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Bibliographic Details
Published in:Bioscience, biotechnology, and biochemistry biotechnology, and biochemistry, 2012, Vol.76 (5), p.1011-1014
Main Authors: WAKUTSU, Masaki, TSUNODA, Nobuyo, MOCHI, Yasuki, NUMAJIRI, Mitsuki, SHIBA, Sachiko, MURAKI, Etsuko, KASONO, Keizo
Format: Article
Language:English
Subjects:
adiponectin
Adiponectin - blood
Adipose Tissue, White - drug effects
Adipose Tissue, White - metabolism
Animals
Biological and medical sciences
Body Weight - drug effects
Cattle
Diet, High-Fat
Dietary Fats - administration & dosage
dyslipidemia
Dyslipidemias - blood
Dyslipidemias - drug therapy
Dyslipidemias - etiology
Fats - pharmacology
fish oil
Fish Oils - pharmacology
food restriction
Fundamental and applied biological sciences. Psychology
Liver - drug effects
Liver - metabolism
Mice
Mice, Obese
Weight Loss - drug effects
weight reduction
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Summary:The effect on weight reduction of fish oil combined with food restriction in comparison with that of beef tallow was investigated in high-fat diet-induced obese KKAy mice. Although the reduction of body and white adipose tissue weight was similar in the two groups, fish oil increased adiponectin levels in the plasma, improved dyslipidemia accompanied by suppression of lipid synthesis in the liver when compared with beef tallow.
ISSN:0916-8451
1347-6947
DOI:10.1271/bbb.110743