Preoperative serum albumin is an independent prognostic predictor of survival in ovarian cancer

Ovarian cancer is associated with high mortality due to asymptomatic nature of the disease and advance stage at presentation. In advanced stages, it is associated with cachexia and ascites leading to malnutrition. Nutritional status of a patient with cancer has been well known to be associated with...

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Bibliographic Details
Published in:Medical oncology (Northwood, London, England) London, England), 2012-09, Vol.29 (3), p.2005-2009
Main Authors: Asher, V., Lee, J., Bali, A.
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Biomarkers, Tumor - blood
Female
Hematology
Humans
Internal Medicine
Kaplan-Meier Estimate
Medicine
Medicine & Public Health
Middle Aged
Neoplasm Grading
Neoplasm Staging
Oncology
Original Paper
Ovarian cancer
Ovarian Neoplasms - blood
Ovarian Neoplasms - mortality
Ovarian Neoplasms - pathology
Pathology
Preoperative Period
Prognosis
Serum Albumin - analysis
Young Adult
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Summary:Ovarian cancer is associated with high mortality due to asymptomatic nature of the disease and advance stage at presentation. In advanced stages, it is associated with cachexia and ascites leading to malnutrition. Nutritional status of a patient with cancer has been well known to be associated with survival and can be assessed by level of albumin in blood. Therefore, in this study, we sought to determine preoperative serum albumin as prognostic predictor of survival in patients with ovarian cancer. Preoperative serum albumin was determined in 235 patients undergoing surgery for ovarian cancer at Royal Derby Hospital. The prognostic predictive value of serum albumin, along with other prognostic markers was then analysed using univariate and multivariate analyses. Low serum albumin was associated with poor survival ( P  
ISSN:1357-0560
1559-131X
DOI:10.1007/s12032-011-0019-5