A comparison of non-HDL and LDL cholesterol goal attainment in a large, multinational patient population: The Lipid Treatment Assessment Project 2

• Published in: Atherosclerosis 2012-09, Vol.224 (1), p.150-153
• Main Authors: Santos, Raul D, Waters, David D, Tarasenko, Lisa, Messig, Michael, Jukema, J. Wouter, Chiang, Cheng-Wen, Ferrieres, Jean, Foody, JoAnne M
• Format: Article
• Language: English
• Subjects: Adult; Aged; atherosclerosis; Atherosclerosis (general aspects, experimental research); Biological and medical sciences; Blood and lymphatic vessels; Canada; Cardiology. Vascular system; Cardiovascular; Cholesterol, HDL - blood; Cholesterol, LDL - blood; coronary disease; Coronary Disease - drug therapy; Coronary heart disease; Dyslipidemias - drug therapy; Europe; Female; General and cellular metabolism. Vitamins; Humans; hyperlipidemia; Hypolipidemic Agents - therapeutic use; Latin America; LDL-cholesterol; low density lipoprotein cholesterol; Male; Medical sciences; Middle Aged; Non-HDL cholesterol; patients; Pharmacology. Drug treatments; Risk Factors; therapeutics; Treatment Outcome; triacylglycerols; Triglycerides; Triglycerides - blood; United States
• ISSN: 0021-9150; 1879-1484
• DOI: 10.1016/j.atherosclerosis.2012.06.052

Abstract Objective This study evaluated the success in attaining non-HDL-cholesterol (non-HDL-C) goals in the multinational L-TAP 2 study. Methods 9955 patients ≥20 years of age with dyslipidemia on stable lipid-lowering therapy were enrolled from nine countries. Results Success rates for non-HDL-C goals were 86% in low, 70% in moderate, and 52% in high-risk patients (63% overall). In patients with triglycerides of >200 mg/dL success rates for non-HDL-C goals were 35% vs. 69% in those with ≤200 mg/dL ( p