Effect of Obstructive Sleep Apnea on Heart Rate, Heart Rate Recovery and QTc and P-wave Dispersion in Newly Diagnosed Untreated Patients

Abstract Introduction Obstructive sleep apnea syndrome (OSAS) is associated with autonomic dysfunction, whereas increased heart rate (HR), HR recovery time (HRR-1), QT-corrected interval (QTc) and P-wave dispersion (Pd) are associated with cardiovascular events. The aim of the current investigation...

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Bibliographic Details
Published in:The American journal of the medical sciences 2012-09, Vol.344 (3), p.180-185
Main Authors: Çiçek, Davran, MD, Gökay, Seher, MD, Lakadamyali, Hüseyin, MD, Sapmaz, Ismail, MD, Muderrisoglu, Haldun, MD
Format: Article
Language:English
Subjects:
Adult
Aged
Biological and medical sciences
Cardiovascular Diseases - diagnosis
Cardiovascular Diseases - physiopathology
Echocardiography
Electrocardiography
Electrocardiography, Ambulatory
Exercise Test
Female
General aspects
Heart - physiopathology
Heart Rate
Heart rate recovery time
Humans
Internal Medicine
Male
Medical sciences
Middle Aged
Obstructive sleep apnea syndrome
P-wave dispersion
Pneumology
Polysomnography
Prospective Studies
QT-corrected interval
Respiratory system : syndromes and miscellaneous diseases
Risk Factors
Severity of Illness Index
Sleep
Sleep Apnea, Obstructive - diagnosis
Sleep Apnea, Obstructive - physiopathology
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Summary:Abstract Introduction Obstructive sleep apnea syndrome (OSAS) is associated with autonomic dysfunction, whereas increased heart rate (HR), HR recovery time (HRR-1), QT-corrected interval (QTc) and P-wave dispersion (Pd) are associated with cardiovascular events. The aim of the current investigation was to clarify the influence of OSAS severity on these cardiac parameters. Methods Ninety newly diagnosed and untreated patients with OSAS underwent overnight polysomnography and cardiopulmonary exercise testing, including HRR-1, echocardiography, 24-hour Holter electrocardiography, surface electrocardiogram (ECG) and measurement of several metabolic parameters. The patients were divided into the following 4 groups: 26 with apnea-hypopnea index (AHI)
ISSN:0002-9629
1538-2990
DOI:10.1097/MAJ.0b013e318239a67f