Coordinated gene expression in adipose tissue and liver differs between cows with high or low NEFA concentrations in early lactation

Dairy cows with high and low plasma non‐esterified fatty acid (NEFA) concentrations in early lactation were compared for plasma parameters and mRNA expression of genes in liver and subcutaneous adipose tissue. The study involved 16 multiparous dairy cows with a plasma NEFA concentration of >500 μ...

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Bibliographic Details
Published in:Journal of animal physiology and animal nutrition 2012-02, Vol.96 (1), p.137-147
Main Authors: van Dorland, H. A, Sadri, H, Morel, I, Bruckmaier, R. M
Format: Article
Language:English
Subjects:
Abundance
Adipose tissue
Adipose Tissue - metabolism
Animals
blood plasma
body condition
carnitine palmitoyltransferase
cattle
Cattle - blood
Cattle - metabolism
correlation
Dairies
dairy cows
Dairying
dehydrogenase
DNA, Complementary
early lactation
Fatty acids
Fatty Acids, Nonesterified - blood
Female
free fatty acids
Gene expression
Gene Expression Regulation - drug effects
genes
Hormones
Insulin
Ketogenesis
Lactation
Lipid metabolism
Liver
Liver - metabolism
messenger RNA
Metabolites
Milk
milk fat yield
milking
mRNA
Oxidation
subcutaneous fat
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Summary:Dairy cows with high and low plasma non‐esterified fatty acid (NEFA) concentrations in early lactation were compared for plasma parameters and mRNA expression of genes in liver and subcutaneous adipose tissue. The study involved 16 multiparous dairy cows with a plasma NEFA concentration of >500 μmol/l [n = 8, high NEFA (HNEFA)] and
ISSN:0931-2439
1439-0396
DOI:10.1111/j.1439-0396.2011.01130.x