A new acylated flavonoid glycoside from the flowers of Camellia nitidissima and its effect on the induction of apoptosis in human lymphoma U937 cells

From the EtOH extract of the flowers of Camellia nitidissima Chi, a new acylated flavonoid glycoside, quercetin 7-O-(6″-O-E-caffeoyl)-β-d-glucopyranoside (1), has been isolated, together with three known flavonoids: quercetin (2), quercetin 3-O-β-d-glucopyranoside (3), and quercetin 7-O-β-d-glucopyr...

Full description

Saved in:
Bibliographic Details
Published in:Journal of asian natural products research 2012-08, Vol.14 (8), p.799-804
Main Authors: Peng, Xiao, Yu, Da-Yong, Feng, Bao-Min, Wang, Yong-Qi, Shi, Li-Ying
Format: Article
Language:English
Subjects:
Antineoplastic Agents, Phytogenic - chemistry
Antineoplastic Agents, Phytogenic - isolation & purification
Antineoplastic Agents, Phytogenic - pharmacology
Apoptosis
Apoptosis - drug effects
Biological and medical sciences
Camellia - chemistry
Camellia nitidissima
Cells
cytotoxicity
Drug Screening Assays, Antitumor
Drugs, Chinese Herbal - chemistry
Drugs, Chinese Herbal - isolation & purification
Drugs, Chinese Herbal - pharmacology
flavonoid glycoside
Flowers & plants
Flowers - chemistry
General pharmacology
Glucosides - chemistry
Glucosides - isolation & purification
Glucosides - pharmacology
Humans
Medical sciences
Molecular Structure
Nuclear Magnetic Resonance, Biomolecular
Pharmacognosy. Homeopathy. Health food
Pharmacology. Drug treatments
Quercetin - analogs & derivatives
Quercetin - chemistry
Quercetin - isolation & purification
Quercetin - pharmacology
Stereoisomerism
U937 Cells
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:From the EtOH extract of the flowers of Camellia nitidissima Chi, a new acylated flavonoid glycoside, quercetin 7-O-(6″-O-E-caffeoyl)-β-d-glucopyranoside (1), has been isolated, together with three known flavonoids: quercetin (2), quercetin 3-O-β-d-glucopyranoside (3), and quercetin 7-O-β-d-glucopyranoside (4). Their structures were elucidated on the basis of spectroscopic analysis. Compound 1 was shown to inhibit proliferation and to induce apoptosis of human lymphoma U937 cells.
ISSN:1028-6020
1477-2213
DOI:10.1080/10286020.2012.691475