Tigecycline Pharmacokinetics in Subjects With Various Degrees of Renal Function

The pharmacokinetic parameters of tigecycline were assessed in subjects with severe renal impairment (creatinine clearance

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Bibliographic Details
Published in:Journal of clinical pharmacology 2012-09, Vol.52 (9), p.1379-1387
Main Authors: Korth-Bradley, Joan M., Troy, Steven M., Matschke, Kyle, Muralidharan, Gopal, Fruncillo, Richard J., Speth, John L., Raible, Donald G.
Format: Article
Language:English
Subjects:
Adult
Aged
Anti-Bacterial Agents - blood
Anti-Bacterial Agents - pharmacokinetics
Anti-Bacterial Agents - urine
Chromatography
Female
glycylcyclines
Hemodialysis
Humans
Kidney - metabolism
Male
Middle Aged
Minocycline - analogs & derivatives
Minocycline - blood
Minocycline - pharmacokinetics
Minocycline - urine
pharmacokinetics
Renal Dialysis
renal impairment
Renal Insufficiency - metabolism
Renal Insufficiency - physiopathology
tigecycline
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Description
Summary:The pharmacokinetic parameters of tigecycline were assessed in subjects with severe renal impairment (creatinine clearance
ISSN:0091-2700
1552-4604
DOI:10.1177/0091270011416938