Granulomatous orchitis in a pre-pubertal school-aged child: Differential diagnosis dilemmas

Abstract A 6-year-old male presented with testicular growth and persistent chronic orchiepididymitis with high inflammatory markers (C reactive protein and erythrocyte sedimentation rate). Biopsies of the testes and epididymides showed bilateral epididymal and testicular granulomata, testicular fibr...

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Bibliographic Details
Published in:Journal of pediatric urology 2012-10, Vol.8 (5), p.e51-e54
Main Authors: Jesus, Lisieux E, Rocha, Kátia L.M, Caldas, Maria L.R, Fonseca, Elissa
Format: Article
Language:English
Subjects:
Biopsy
Child
Diagnosis, Differential
Granuloma - diagnosis
Granulomatous orchitis
Humans
Male
Orchiepididymitis
Orchitis - diagnosis
Pediatrics
Testis - diagnostic imaging
Testis - pathology
Tomography, X-Ray Computed
Ultrasonography, Doppler
Urology
Vasculitis
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Summary:Abstract A 6-year-old male presented with testicular growth and persistent chronic orchiepididymitis with high inflammatory markers (C reactive protein and erythrocyte sedimentation rate). Biopsies of the testes and epididymides showed bilateral epididymal and testicular granulomata, testicular fibrosis and chronic inflammatory infiltration, and the histological diagnosis was granulomatous orchitis. The symptoms receded with oral corticosteroids. Although rare, granulomatous orchitis is a possible diagnosis in children presenting testicular enlargement. It is important to differentiate it from testicular tumors (if necessary with testicular biopsy) and to investigate its association with systemic vasculitis and infectious diseases.
ISSN:1477-5131
1873-4898
DOI:10.1016/j.jpurol.2012.03.011