Non-Hodgkin lymphoma

Summary Lymphomas are solid tumours of the immune system. Hodgkin's lymphoma accounts for about 10% of all lymphomas, and the remaining 90% are referred to as non-Hodgkin lymphoma. Non-Hodgkin lymphomas have a wide range of histological appearances and clinical features at presentation, which c...

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Bibliographic Details
Published in:The Lancet (British edition) 2012-09, Vol.380 (9844), p.848-857
Main Authors: Shankland, Kate R, Dr, Armitage, James O, Prof, Hancock, Barry W, Prof
Format: Article
Language:English
Subjects:
Antineoplastic Agents - therapeutic use
Autoimmune diseases
Biological and medical sciences
Cancer
Classification
DNA repair
General aspects
Hematologic and hematopoietic diseases
Herpes viruses
Humans
Immune system
Infections
Internal Medicine
Kinases
Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis
Lymphocytes
Lymphoma
Lymphoma, Non-Hodgkin - classification
Lymphoma, Non-Hodgkin - diagnosis
Lymphoma, Non-Hodgkin - drug therapy
Lymphoma, Non-Hodgkin - epidemiology
Medical sciences
Neoplasm Staging
Prognosis
Transplants & implants
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Summary:Summary Lymphomas are solid tumours of the immune system. Hodgkin's lymphoma accounts for about 10% of all lymphomas, and the remaining 90% are referred to as non-Hodgkin lymphoma. Non-Hodgkin lymphomas have a wide range of histological appearances and clinical features at presentation, which can make diagnosis difficult. Lymphomas are not rare, and most physicians, irrespective of their specialty, will probably have come across a patient with lymphoma. Timely diagnosis is important because effective, and often curative, therapies are available for many subtypes. In this Seminar we discuss advances in the understanding of the biology of these malignancies and new, available treatments.
ISSN:0140-6736
1474-547X
DOI:10.1016/S0140-6736(12)60605-9