Immune response in mice following intrabrain injections of allogeneic spleen or brain cells

Cytotoxic activity of spleen lymphocytes and lymphatic knots was studied. Accumulation of anibodies in blood serum of recipient in response to intrabrain injection of the antigen was investigated. Cellular and humoral immune response of mice developed with the intrabrain injection ofalohenic cells....

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Bibliographic Details
Published in:Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) Ukraine : 1994), 2012, Vol.58 (3), p.27-31
Main Authors: Lisianyĭ, M I, Kliuchnykova, A I
Format: Article
Language:eng ; ukr
Subjects:
Animals
Brain - cytology
Brain - immunology
Cell Separation
Cell Transplantation
Embryo, Mammalian
Injections, Intraventricular
Isoantibodies - blood
Isoantibodies - immunology
Isoantigens - blood
Isoantigens - immunology
Lymphocytes - immunology
Mice
Mice, Inbred C57BL
Spleen - cytology
Spleen - immunology
Transplantation, Homologous
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Summary:Cytotoxic activity of spleen lymphocytes and lymphatic knots was studied. Accumulation of anibodies in blood serum of recipient in response to intrabrain injection of the antigen was investigated. Cellular and humoral immune response of mice developed with the intrabrain injection ofalohenic cells. The data obtained suggest that there is no isolation of the brain, because antigen injection to the brain is able to induce the immune reaction.
ISSN:2522-9028
2522-9036
DOI:10.15407/fz58.03.027