Noncontact Wide-Field Multispectral Imaging for Tissue Characterization

Imaging of large tissue areas (>;5 cm 2 ) is often desired in clinical settings, e.g., of tissue oxygenation. Intrinsic contrasts such as absorption and scattering changes have the potential to enhance diagnostics and help monitor diseased tissue. An overview of existing noncontact multispectral...

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Bibliographic Details
Published in:IEEE journal of selected topics in quantum electronics 2012-07, Vol.18 (4), p.1343-1354
Main Authors: Kainerstorfer, J. M., Smith, P. D., Gandjbakhche, A. H.
Format: Article
Language:English
Subjects:
Absorption
Biophotonics
Diffusion
Imaging
Instrumentation
Mathematical models
Monitors
multispectral imaging
optical imaging
Optical reflection
Optical scattering
Reflectance
Reflectivity
Scattering
Skin
wide-field imaging
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Summary:Imaging of large tissue areas (>;5 cm 2 ) is often desired in clinical settings, e.g., of tissue oxygenation. Intrinsic contrasts such as absorption and scattering changes have the potential to enhance diagnostics and help monitor diseased tissue. An overview of existing noncontact multispectral diffuse reflectance imaging modalities for tissue characterization based on intrinsic optical contrast due to absorption and scattering properties of tissue is given here. Also, an overview of instrumentation advances, modeling approaches, applications, and ongoing work is described, primarily in, but not limited to, skin imaging, demonstrating the benefits and limitations of wide-field diffuse reflectance imaging.
ISSN:1077-260X
1558-4542
DOI:10.1109/JSTQE.2011.2175708