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Sodium methoxide: a simple but highly efficient catalyst for the direct amidation of esters

A simple NaOMe catalyst provides superior accessibility to a wide variety of functionalized amides including peptides through direct amination of esters in an atom-economical and environmentally benign way.

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Bibliographic Details
Published in:Chemical communications (Cambridge, England) England), 2012-01, Vol.48 (44), p.5434-5436
Main Authors: Ohshima, Takashi, Hayashi, Yukiko, Agura, Kazushi, Fujii, Yuka, Yoshiyama, Asako, Mashima, Kazushi
Format: Article
Language:English
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Summary:A simple NaOMe catalyst provides superior accessibility to a wide variety of functionalized amides including peptides through direct amination of esters in an atom-economical and environmentally benign way.
ISSN:1359-7345
1364-548X
DOI:10.1039/c2cc32153j