An analysis of the survival rate after radiotherapy in lung cancer patients with bone metastasis: is there an optimal subgroup to be treated with high-dose radiation therapy?

We investigated the prognostic factors after radiotherapy for bone metastasis from lung cancer while taking the recent findings in the treatment of such cases into consideration. A total of 132 patients with bone metastases from pathologically confirmed lung cancer were evaluated regarding the follo...

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Bibliographic Details
Published in:Neoplasma 2012, Vol.59 (6), p.650-657
Main Authors: Komatsu, T, Kunieda, E, Oizumi, Y, Tamai, Y, Akiba, T
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Bone Neoplasms - mortality
Bone Neoplasms - radiotherapy
Bone Neoplasms - secondary
Female
Humans
Lung Neoplasms - mortality
Lung Neoplasms - pathology
Male
Middle Aged
Prognosis
Receptor, Epidermal Growth Factor - antagonists & inhibitors
Survival Rate
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Summary:We investigated the prognostic factors after radiotherapy for bone metastasis from lung cancer while taking the recent findings in the treatment of such cases into consideration. A total of 132 patients with bone metastases from pathologically confirmed lung cancer were evaluated regarding the following potential prognostic factors: treatment for primary site (surgery vs. other), treatment site (spine vs. other), number of bone metastases (solitary vs. multiple), number of metastatic organs (0 vs. 1 vs. ≥2), neurological symptoms (no symptoms vs. numbness vs. paresis), degree of pain (no pain vs. mild pain vs. severe pain), performance status [PS] (0-1 vs. ≥2), biological effective dose [BED] (≥40 Gy vs.
ISSN:0028-2685
DOI:10.4149/neo_2012_082