Loading…
Tomographic imaging of the spleen: the role of morphological and metabolic features in differentiating benign from malignant diseases
Abstract To evaluate the tomographic features in differentiating benign from malignant splenic diseases, 54 patients with a cytohistological examination and a contrast-enhanced multidetector computed tomography (ce-MDCT) and/or positron emission tomography/computed tomography (PET/CT) were retrospec...
Saved in:
| Published in: | Clinical imaging 2012-09, Vol.36 (5), p.559-567 |
|---|---|
| Main Authors: | , , , , , , , , , |
| Format: | Article |
| Language: | English |
| Subjects: | |
| Citations: | Items that this one cites Items that cite this one |
| Online Access: | Get full text |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| cited_by | cdi_FETCH-LOGICAL-c484t-a7158e6dbab2bbb4c921d7a8a5d30bb3e02e9ec3191f9b190013bd1ca92c23713 |
|---|---|
| cites | cdi_FETCH-LOGICAL-c484t-a7158e6dbab2bbb4c921d7a8a5d30bb3e02e9ec3191f9b190013bd1ca92c23713 |
| container_end_page | 567 |
| container_issue | 5 |
| container_start_page | 559 |
| container_title | Clinical imaging |
| container_volume | 36 |
| creator | Mainenti, Pier Paolo Iodice, Delfina Cozzolino, Immacolata Segreto, Sabrina Capece, Sergio Sica, Giacomo Magliulo, Mario Ciancia, Giuseppe Pace, Leonardo Salvatore, Marco |
| description | Abstract To evaluate the tomographic features in differentiating benign from malignant splenic diseases, 54 patients with a cytohistological examination and a contrast-enhanced multidetector computed tomography (ce-MDCT) and/or positron emission tomography/computed tomography (PET/CT) were retrospectively selected. Significant associations were observed between ce-MDCT Pattern 3 (focal hyperdense lesion) and Pattern 4 (infarcts/cysts) as well as PET/CT Pattern 3 (focal photopenia/diffuse uptake |
| doi_str_mv | 10.1016/j.clinimag.2012.01.015 |
| format | article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1038614560</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0899707112000216</els_id><sourcerecordid>2746912981</sourcerecordid><originalsourceid>FETCH-LOGICAL-c484t-a7158e6dbab2bbb4c921d7a8a5d30bb3e02e9ec3191f9b190013bd1ca92c23713</originalsourceid><addsrcrecordid>eNqNks9qFTEUxoMo9rb6CiXgxs1c82cmM3EhlmJVKLiwrkOSOTM310xyTWaEPoDvbaa3VehG4ZCE8Pu-cPIdhM4p2VJCxZv91noX3KTHLSOUbQkt1TxBG9q1vKprKZ-iDemkrFrS0hN0mvOeFKGs2-fohDHJCBdsg37dxCmOSR92zuLVzoURxwHPO8D54AHC27tzih7W-ymmwy76ODqrPdahxxPM2kRf5APoeUmQsQu4d8MACcLs9LxaGghuDHhIccKT9uWsw1yoDDpDfoGeDdpneHm_n6FvVx9uLj9V118-fr68uK5s3dVzpVvadCB6ow0zxtRWMtq3utNNz4kxHAgDCZZTSQdpqCwNc9NTqyWzjLeUn6HXR99Dij8WyLOaXLbgvQ4Ql6wo4Z2gdSPI_6BNw4SUoqCvHqH7uKRQGjlSoqysUOJI2RRzTjCoQyofnm4LpNZM1V49ZKrWTBWhpZoiPL-3X8wE_R_ZQ4gFeH8EoHzdTwdJZesgWOhdAjurPrp_v_HukcUdVjL-DreQ__ajctGor-tkrYNFGSGEUcF_A59YzDA</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1035561032</pqid></control><display><type>article</type><title>Tomographic imaging of the spleen: the role of morphological and metabolic features in differentiating benign from malignant diseases</title><source>ScienceDirect Freedom Collection 2022-2024</source><creator>Mainenti, Pier Paolo ; Iodice, Delfina ; Cozzolino, Immacolata ; Segreto, Sabrina ; Capece, Sergio ; Sica, Giacomo ; Magliulo, Mario ; Ciancia, Giuseppe ; Pace, Leonardo ; Salvatore, Marco</creator><creatorcontrib>Mainenti, Pier Paolo ; Iodice, Delfina ; Cozzolino, Immacolata ; Segreto, Sabrina ; Capece, Sergio ; Sica, Giacomo ; Magliulo, Mario ; Ciancia, Giuseppe ; Pace, Leonardo ; Salvatore, Marco</creatorcontrib><description>Abstract To evaluate the tomographic features in differentiating benign from malignant splenic diseases, 54 patients with a cytohistological examination and a contrast-enhanced multidetector computed tomography (ce-MDCT) and/or positron emission tomography/computed tomography (PET/CT) were retrospectively selected. Significant associations were observed between ce-MDCT Pattern 3 (focal hyperdense lesion) and Pattern 4 (infarcts/cysts) as well as PET/CT Pattern 3 (focal photopenia/diffuse uptake<liver) and benign pathologies, and between ce-MDCT Pattern 1 (splenomegaly without focal lesions) and Pattern 2 (focal hypodense lesion) as well as PET/CT Pattern 1 (diffuse uptake≥liver) and Pattern 2 (focal increased uptake) and malignant diseases. No significant association between benign or malignant diseases and spleen volumes and maximum standardized uptake value (SUVmax ) as well as lesion characteristics was observed. The metabolic data do not improve the performance of morphological patterns.</description><identifier>ISSN: 0899-7071</identifier><identifier>EISSN: 1873-4499</identifier><identifier>DOI: 10.1016/j.clinimag.2012.01.015</identifier><identifier>PMID: 22920362</identifier><identifier>CODEN: CLIMEB</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Abdomen ; Adolescent ; Adult ; Aged ; Benign disease ; Child ; Contrast Media ; Cysts ; Diagnosis, Differential ; Disease ; Female ; Humans ; Iohexol - analogs & derivatives ; Lymphoma ; Male ; Malignant disease ; Medical imaging ; Middle Aged ; Multimodal Imaging - methods ; Pathology ; PET/CT ; Positron-Emission Tomography ; Radiographic Image Interpretation, Computer-Assisted ; Radiology ; Retrospective Studies ; Spleen ; Splenic Diseases - diagnostic imaging ; Splenic Diseases - pathology ; Tomography ; Tomography, X-Ray Computed - methods ; Work stations</subject><ispartof>Clinical imaging, 2012-09, Vol.36 (5), p.559-567</ispartof><rights>Elsevier Inc.</rights><rights>2012 Elsevier Inc.</rights><rights>Copyright © 2012 Elsevier Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c484t-a7158e6dbab2bbb4c921d7a8a5d30bb3e02e9ec3191f9b190013bd1ca92c23713</citedby><cites>FETCH-LOGICAL-c484t-a7158e6dbab2bbb4c921d7a8a5d30bb3e02e9ec3191f9b190013bd1ca92c23713</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22920362$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Mainenti, Pier Paolo</creatorcontrib><creatorcontrib>Iodice, Delfina</creatorcontrib><creatorcontrib>Cozzolino, Immacolata</creatorcontrib><creatorcontrib>Segreto, Sabrina</creatorcontrib><creatorcontrib>Capece, Sergio</creatorcontrib><creatorcontrib>Sica, Giacomo</creatorcontrib><creatorcontrib>Magliulo, Mario</creatorcontrib><creatorcontrib>Ciancia, Giuseppe</creatorcontrib><creatorcontrib>Pace, Leonardo</creatorcontrib><creatorcontrib>Salvatore, Marco</creatorcontrib><title>Tomographic imaging of the spleen: the role of morphological and metabolic features in differentiating benign from malignant diseases</title><title>Clinical imaging</title><addtitle>Clin Imaging</addtitle><description>Abstract To evaluate the tomographic features in differentiating benign from malignant splenic diseases, 54 patients with a cytohistological examination and a contrast-enhanced multidetector computed tomography (ce-MDCT) and/or positron emission tomography/computed tomography (PET/CT) were retrospectively selected. Significant associations were observed between ce-MDCT Pattern 3 (focal hyperdense lesion) and Pattern 4 (infarcts/cysts) as well as PET/CT Pattern 3 (focal photopenia/diffuse uptake<liver) and benign pathologies, and between ce-MDCT Pattern 1 (splenomegaly without focal lesions) and Pattern 2 (focal hypodense lesion) as well as PET/CT Pattern 1 (diffuse uptake≥liver) and Pattern 2 (focal increased uptake) and malignant diseases. No significant association between benign or malignant diseases and spleen volumes and maximum standardized uptake value (SUVmax ) as well as lesion characteristics was observed. The metabolic data do not improve the performance of morphological patterns.</description><subject>Abdomen</subject><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Benign disease</subject><subject>Child</subject><subject>Contrast Media</subject><subject>Cysts</subject><subject>Diagnosis, Differential</subject><subject>Disease</subject><subject>Female</subject><subject>Humans</subject><subject>Iohexol - analogs & derivatives</subject><subject>Lymphoma</subject><subject>Male</subject><subject>Malignant disease</subject><subject>Medical imaging</subject><subject>Middle Aged</subject><subject>Multimodal Imaging - methods</subject><subject>Pathology</subject><subject>PET/CT</subject><subject>Positron-Emission Tomography</subject><subject>Radiographic Image Interpretation, Computer-Assisted</subject><subject>Radiology</subject><subject>Retrospective Studies</subject><subject>Spleen</subject><subject>Splenic Diseases - diagnostic imaging</subject><subject>Splenic Diseases - pathology</subject><subject>Tomography</subject><subject>Tomography, X-Ray Computed - methods</subject><subject>Work stations</subject><issn>0899-7071</issn><issn>1873-4499</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><recordid>eNqNks9qFTEUxoMo9rb6CiXgxs1c82cmM3EhlmJVKLiwrkOSOTM310xyTWaEPoDvbaa3VehG4ZCE8Pu-cPIdhM4p2VJCxZv91noX3KTHLSOUbQkt1TxBG9q1vKprKZ-iDemkrFrS0hN0mvOeFKGs2-fohDHJCBdsg37dxCmOSR92zuLVzoURxwHPO8D54AHC27tzih7W-ymmwy76ODqrPdahxxPM2kRf5APoeUmQsQu4d8MACcLs9LxaGghuDHhIccKT9uWsw1yoDDpDfoGeDdpneHm_n6FvVx9uLj9V118-fr68uK5s3dVzpVvadCB6ow0zxtRWMtq3utNNz4kxHAgDCZZTSQdpqCwNc9NTqyWzjLeUn6HXR99Dij8WyLOaXLbgvQ4Ql6wo4Z2gdSPI_6BNw4SUoqCvHqH7uKRQGjlSoqysUOJI2RRzTjCoQyofnm4LpNZM1V49ZKrWTBWhpZoiPL-3X8wE_R_ZQ4gFeH8EoHzdTwdJZesgWOhdAjurPrp_v_HukcUdVjL-DreQ__ajctGor-tkrYNFGSGEUcF_A59YzDA</recordid><startdate>20120901</startdate><enddate>20120901</enddate><creator>Mainenti, Pier Paolo</creator><creator>Iodice, Delfina</creator><creator>Cozzolino, Immacolata</creator><creator>Segreto, Sabrina</creator><creator>Capece, Sergio</creator><creator>Sica, Giacomo</creator><creator>Magliulo, Mario</creator><creator>Ciancia, Giuseppe</creator><creator>Pace, Leonardo</creator><creator>Salvatore, Marco</creator><general>Elsevier Inc</general><general>Elsevier Limited</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>8FD</scope><scope>FR3</scope><scope>K9.</scope><scope>M7Z</scope><scope>P64</scope><scope>7X8</scope><scope>7QO</scope></search><sort><creationdate>20120901</creationdate><title>Tomographic imaging of the spleen: the role of morphological and metabolic features in differentiating benign from malignant diseases</title><author>Mainenti, Pier Paolo ; Iodice, Delfina ; Cozzolino, Immacolata ; Segreto, Sabrina ; Capece, Sergio ; Sica, Giacomo ; Magliulo, Mario ; Ciancia, Giuseppe ; Pace, Leonardo ; Salvatore, Marco</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c484t-a7158e6dbab2bbb4c921d7a8a5d30bb3e02e9ec3191f9b190013bd1ca92c23713</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Abdomen</topic><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>Benign disease</topic><topic>Child</topic><topic>Contrast Media</topic><topic>Cysts</topic><topic>Diagnosis, Differential</topic><topic>Disease</topic><topic>Female</topic><topic>Humans</topic><topic>Iohexol - analogs & derivatives</topic><topic>Lymphoma</topic><topic>Male</topic><topic>Malignant disease</topic><topic>Medical imaging</topic><topic>Middle Aged</topic><topic>Multimodal Imaging - methods</topic><topic>Pathology</topic><topic>PET/CT</topic><topic>Positron-Emission Tomography</topic><topic>Radiographic Image Interpretation, Computer-Assisted</topic><topic>Radiology</topic><topic>Retrospective Studies</topic><topic>Spleen</topic><topic>Splenic Diseases - diagnostic imaging</topic><topic>Splenic Diseases - pathology</topic><topic>Tomography</topic><topic>Tomography, X-Ray Computed - methods</topic><topic>Work stations</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Mainenti, Pier Paolo</creatorcontrib><creatorcontrib>Iodice, Delfina</creatorcontrib><creatorcontrib>Cozzolino, Immacolata</creatorcontrib><creatorcontrib>Segreto, Sabrina</creatorcontrib><creatorcontrib>Capece, Sergio</creatorcontrib><creatorcontrib>Sica, Giacomo</creatorcontrib><creatorcontrib>Magliulo, Mario</creatorcontrib><creatorcontrib>Ciancia, Giuseppe</creatorcontrib><creatorcontrib>Pace, Leonardo</creatorcontrib><creatorcontrib>Salvatore, Marco</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Biochemistry Abstracts 1</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><collection>Biotechnology Research Abstracts</collection><jtitle>Clinical imaging</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mainenti, Pier Paolo</au><au>Iodice, Delfina</au><au>Cozzolino, Immacolata</au><au>Segreto, Sabrina</au><au>Capece, Sergio</au><au>Sica, Giacomo</au><au>Magliulo, Mario</au><au>Ciancia, Giuseppe</au><au>Pace, Leonardo</au><au>Salvatore, Marco</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Tomographic imaging of the spleen: the role of morphological and metabolic features in differentiating benign from malignant diseases</atitle><jtitle>Clinical imaging</jtitle><addtitle>Clin Imaging</addtitle><date>2012-09-01</date><risdate>2012</risdate><volume>36</volume><issue>5</issue><spage>559</spage><epage>567</epage><pages>559-567</pages><issn>0899-7071</issn><eissn>1873-4499</eissn><coden>CLIMEB</coden><abstract>Abstract To evaluate the tomographic features in differentiating benign from malignant splenic diseases, 54 patients with a cytohistological examination and a contrast-enhanced multidetector computed tomography (ce-MDCT) and/or positron emission tomography/computed tomography (PET/CT) were retrospectively selected. Significant associations were observed between ce-MDCT Pattern 3 (focal hyperdense lesion) and Pattern 4 (infarcts/cysts) as well as PET/CT Pattern 3 (focal photopenia/diffuse uptake<liver) and benign pathologies, and between ce-MDCT Pattern 1 (splenomegaly without focal lesions) and Pattern 2 (focal hypodense lesion) as well as PET/CT Pattern 1 (diffuse uptake≥liver) and Pattern 2 (focal increased uptake) and malignant diseases. No significant association between benign or malignant diseases and spleen volumes and maximum standardized uptake value (SUVmax ) as well as lesion characteristics was observed. The metabolic data do not improve the performance of morphological patterns.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>22920362</pmid><doi>10.1016/j.clinimag.2012.01.015</doi><tpages>9</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0899-7071 |
| ispartof | Clinical imaging, 2012-09, Vol.36 (5), p.559-567 |
| issn | 0899-7071 1873-4499 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1038614560 |
| source | ScienceDirect Freedom Collection 2022-2024 |
| subjects | Abdomen Adolescent Adult Aged Benign disease Child Contrast Media Cysts Diagnosis, Differential Disease Female Humans Iohexol - analogs & derivatives Lymphoma Male Malignant disease Medical imaging Middle Aged Multimodal Imaging - methods Pathology PET/CT Positron-Emission Tomography Radiographic Image Interpretation, Computer-Assisted Radiology Retrospective Studies Spleen Splenic Diseases - diagnostic imaging Splenic Diseases - pathology Tomography Tomography, X-Ray Computed - methods Work stations |
| title | Tomographic imaging of the spleen: the role of morphological and metabolic features in differentiating benign from malignant diseases |
| url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-24T18%3A56%3A49IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Tomographic%20imaging%20of%20the%20spleen:%20the%20role%20of%20morphological%20and%20metabolic%20features%20in%20differentiating%20benign%20from%20malignant%20diseases&rft.jtitle=Clinical%20imaging&rft.au=Mainenti,%20Pier%20Paolo&rft.date=2012-09-01&rft.volume=36&rft.issue=5&rft.spage=559&rft.epage=567&rft.pages=559-567&rft.issn=0899-7071&rft.eissn=1873-4499&rft.coden=CLIMEB&rft_id=info:doi/10.1016/j.clinimag.2012.01.015&rft_dat=%3Cproquest_cross%3E2746912981%3C/proquest_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c484t-a7158e6dbab2bbb4c921d7a8a5d30bb3e02e9ec3191f9b190013bd1ca92c23713%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=1035561032&rft_id=info:pmid/22920362&rfr_iscdi=true |