Type of axial analgesia does not influence time to vaginal delivery in a Proportional Hazards Model

Objective To create a Proportional Hazards Model of prospective factors associated with time-to-vaginal-delivery (TTVD). Methods We analyzed a group of 144 women undergoing childbirth who received one out of two possible axial analgesia techniques, to find-out factors associated with TTVD. The patie...

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Bibliographic Details
Published in:Archives of gynecology and obstetrics 2012-10, Vol.286 (4), p.873-880
Main Authors: Pascual-Ramírez, Javier, Haya, Javier, Pérez-López, Faustino, Gil Trujillo, Silvia
Format: Article
Language:English
Subjects:
Adolescent
Adult
Anesthesia, Epidural
Anesthesia, Spinal
Childbirth & labor
Delivery, Obstetric - statistics & numerical data
Endocrinology
Female
Gynecology
Human Genetics
Humans
Infant, Newborn
Maternal-Fetal Medicine
Medicine
Medicine & Public Health
Obstetrics/Perinatology/Midwifery
Operative Time
Pregnancy
Proportional Hazards Models
Prospective Studies
Young Adult
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Summary:Objective To create a Proportional Hazards Model of prospective factors associated with time-to-vaginal-delivery (TTVD). Methods We analyzed a group of 144 women undergoing childbirth who received one out of two possible axial analgesia techniques, to find-out factors associated with TTVD. The patients were randomly assigned to receive either a levobupivacaine labor epidural (bolus concentration 0.25 % or less; infusion concentration 0.125 % or less) or a combined spinal–epidural procedure (morphine 0.20 mg, fentanyl 25 µg and hyperbaric bupivacaine 2.5 mg as spinal components) for labor analgesia. The factors initially chosen were: mother age, height and weight, parity, gestational age, newborn weight, type of labor, analgesic procedure, levobupivacaine and fentanyl doses, Bromage scale, pain Numeric Rating Scale, and a satisfaction interview. Cesarean section was the censored variable in our model. A systematic multivariate Cox regression was performed. Results Our Final Model stated that nulliparous women had 2.5 times more chances of having longer TTVD than primiparous ( p  
ISSN:0932-0067
1432-0711
DOI:10.1007/s00404-012-2360-0