Clinical Variables and Neuromonitoring Information (Intracranial Pressure and Brain Tissue Oxygenation) as Predictors of Brain-Death Development After Severe Traumatic Brain Injury

Abstract Background and purpose The aim of this study was to ascertain the role of clinical variables and neuromonitoring data as predictors of brain death (BD) after severe traumatic brain injury (TBI). Patients and methods This prospective observational study involved severe TBI patients admitted...

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Bibliographic Details
Published in:Transplantation proceedings 2012-09, Vol.44 (7), p.2050-2052
Main Authors: Egea-Guerrero, J.J, Gordillo-Escobar, E, Revuelto-Rey, J, Enamorado-Enamorado, J, Vilches-Arenas, A, Pacheco-Sánchez, M, Domínguez-Roldán, J.M, Murillo-Cabezas, F
Format: Article
Language:English
Subjects:
Adult
Biological and medical sciences
Brain Death
Brain Injuries - physiopathology
Female
Fundamental and applied biological sciences. Psychology
Fundamental immunology
Glasgow Coma Scale
Humans
Injuries of the nervous system and the skull. Diseases due to physical agents
Male
Medical sciences
Middle Aged
Monitoring, Physiologic
Prospective Studies
Surgery
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Tissue, organ and graft immunology
Traumas. Diseases due to physical agents
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Summary:Abstract Background and purpose The aim of this study was to ascertain the role of clinical variables and neuromonitoring data as predictors of brain death (BD) after severe traumatic brain injury (TBI). Patients and methods This prospective observational study involved severe TBI patients admitted to the intensive care unit between October 2009 and May 2011. The following variables were recorded: gender, age, reference Glasgow Coma Scale after resuscitation, pupillary reactivity, prehospital hypotension and desaturation, injury severity score, computed tomography (CT) findings, intracranial hypertension, and low brain tissue oxygenation (Pti02) levels (
ISSN:0041-1345
1873-2623
DOI:10.1016/j.transproceed.2012.07.070