Rhodium-Catalyzed [2 + 2] Cycloaddition of Ynamides with Nitroalkenes

In the presence of a diene-ligated rhodium complex, ynamides and nitroalkenes undergo catalytic [2 + 2] cycloadditions to provide cyclobutenamides. The presence of sodium tetraphenylborate was found to be crucial for the reactions to proceed efficiently.

Saved in:
Bibliographic Details
Published in:Organic letters 2012-09, Vol.14 (18), p.4934-4937
Main Authors: Smith, Donna L, Chidipudi, Suresh Reddy, Goundry, William R, Lam, Hon Wai
Format: Article
Language:English
Subjects:
Alkenes - chemistry
Alkynes - chemistry
Amides - chemistry
Catalysis
Cycloaddition Reaction
Molecular Structure
Nitro Compounds - chemical synthesis
Nitro Compounds - chemistry
Rhodium - chemistry
Tetraphenylborate - chemistry
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:In the presence of a diene-ligated rhodium complex, ynamides and nitroalkenes undergo catalytic [2 + 2] cycloadditions to provide cyclobutenamides. The presence of sodium tetraphenylborate was found to be crucial for the reactions to proceed efficiently.
ISSN:1523-7060
1523-7052
DOI:10.1021/ol302259v