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Eczema Herpeticum in Children: Clinical Features and Factors Predictive of Hospitalization

Objective To describe the clinical characteristics of pediatric patients with eczema herpeticum and to determine the predictors of hospitalization, and recurrence and repeat episodes. Study design A retrospective cohort study of patients 0-18 years of age diagnosed with eczema herpeticum between May...

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Bibliographic Details
Published in:The Journal of pediatrics 2012-10, Vol.161 (4), p.671-675
Main Authors: Luca, Nadia Jennifer Chiara, MD, Lara-Corrales, Irene, MD, MSc, Pope, Elena, MD, MSc
Format: Article
Language:English
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Summary:Objective To describe the clinical characteristics of pediatric patients with eczema herpeticum and to determine the predictors of hospitalization, and recurrence and repeat episodes. Study design A retrospective cohort study of patients 0-18 years of age diagnosed with eczema herpeticum between May 2000 and April 2009 was carried out at a tertiary pediatric care center in Canada. Seventy-nine patients were included. The primary outcome was hospitalization; secondary outcomes were recurrent and repeat episodes of eczema herpeticum. Results At presentation, 76% of 79 patients with eczema herpeticum had a generalized eruption, 56% had fever, 37% had systemic symptoms, and 10% had eye involvement (keratoconjunctivitis). Forty-five patients (57%) were hospitalized. Predictors for hospitalization included male sex (OR = 3.09; 95% CI, 1.20-7.95, P = .017), fever (OR = 5.75; 95% CI, 2.17-15.26, P < .001), systemic symptoms (OR = 2.84; 95% CI, 1.06-7.62, P = .035), and age
ISSN:0022-3476
1097-6833
DOI:10.1016/j.jpeds.2012.03.057