Rapid Synthesis of PEGylated Ultrasmall Gadolinium Oxide Nanoparticles for Cell Labeling and Tracking with MRI

Ultrasmall paramagnetic Gd2O3 nanoparticles have been developed as contrast agents for molecular and cellular preclinical MRI procedures. These small particles (mean diameter

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Bibliographic Details
Published in:ACS applied materials & interfaces 2012-09, Vol.4 (9), p.4506-4515
Main Authors: Faucher, Luc, Tremblay, Mélanie, Lagueux, Jean, Gossuin, Yves, Fortin, Marc-André
Format: Article
Language:English
Subjects:
Animals
Brain Neoplasms - diagnosis
Cell Line, Tumor
Cell Survival - drug effects
Cell Tracking
Contrast Media - chemistry
Gadolinium - chemistry
Glioblastoma - diagnosis
Magnetic Resonance Imaging
Male
Metal Nanoparticles - chemistry
Metal Nanoparticles - toxicity
Mice
Particle Size
Polyethylene Glycols - chemistry
Rats
Transplantation, Heterologous
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Description
Summary:Ultrasmall paramagnetic Gd2O3 nanoparticles have been developed as contrast agents for molecular and cellular preclinical MRI procedures. These small particles (mean diameter
ISSN:1944-8244
1944-8252
DOI:10.1021/am3006466