Biomimetic formation of crystalline bone-like apatite layers on spongy materials templated by bile salts aggregates

Since the trabecular bone exhibit sponge-like bicontinuity there is a growing interest in the synthesis of spongy-like sieves for the construction of bio-active implantable materials. Here, we propose a one step sol–gel method for the synthesis of bicontinuous pore silica materials using different b...

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Bibliographic Details
Published in:Journal of materials science 2012-03, Vol.47 (6), p.2837-2844
Main Authors: Fernández-Leyes, Marcos, Verdinelli, Valeria, Hassan, Natalia, Ruso, Juan M., Pieroni, Olga, Schulz, Pablo C., Messina, Paula
Format: Article
Language:English
Subjects:
Aggregates
Apatite
Bile
Biocompatibility
Biomedical materials
Biomimetic materials
Body fluids
Bones
Characterization and Evaluation of Materials
Chemistry and Materials Science
Classical Mechanics
Contact
Correlation
Crystal structure
Crystallography and Scattering Methods
In vitro methods and tests
Materials Science
Morphology
Phosphate minerals
Phosphate rock
Polymer Sciences
Porosity
Silica
Silicon dioxide
Sol-gel processes
Solid Mechanics
Surgical implants
Synthesis
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Summary:Since the trabecular bone exhibit sponge-like bicontinuity there is a growing interest in the synthesis of spongy-like sieves for the construction of bio-active implantable materials. Here, we propose a one step sol–gel method for the synthesis of bicontinuous pore silica materials using different bile salts aqueous mixtures as templates. The influences of the type and amount of bile salt on the synthesis processes are investigated and correlated with the final material morphology. As a final point, their structural properties are interrelated with their ability to induce a bone-like apatite layer in contact with simulated body fluid (SBF). We have confirmed that under specific template conditions, the synthesized material has an open bio-active macropore structure that is blanched in a 3D-disordered sponge-like network similar than those existed in trabecular bone.
ISSN:0022-2461
1573-4803
DOI:10.1007/s10853-011-6113-4