Airway distensibility with lung inflation after allogeneic haematopoietic stem-cell transplantation

Highlights ► We hypothesized that airway distensibility is increased after allogeneic HSCT. ► Respiratory system conductance ( Grs ) was measured by FOT and lung density by CT. ► Grs showed a slight (ranging from 12 to 16%) but significant increase after HSCT. ► Airway distensibility with lung infla...

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Published in:Respiratory physiology & neurobiology 2012-10, Vol.184 (1), p.80-85
Main Authors: Barisione, Giovanni, Pompilio, Pasquale P, Bacigalupo, Andrea, Brusasco, Claudia, Cioè, Alex, Dellacà, Raffaele L, Lamparelli, Teresa, Garlaschi, Alessandro, Pellegrino, Riccardo, Brusasco, Vito
Format: Article
Language:English
Subjects:
Adult
Airway distensibility with lung inflation
Allogeneic haematopoietic stem-cell transplantation
Bronchiolitis obliterans syndrome
Female
Forced oscillation technique
Hematologic Neoplasms - therapy
Hematopoietic Stem Cell Transplantation - adverse effects
Humans
Lung - physiopathology
Lung Compliance
Male
Medical Education
Pulmonary/Respiratory
Respiratory Function Tests
Respiratory system conductance
Transplantation, Homologous
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Summary:Highlights ► We hypothesized that airway distensibility is increased after allogeneic HSCT. ► Respiratory system conductance ( Grs ) was measured by FOT and lung density by CT. ► Grs showed a slight (ranging from 12 to 16%) but significant increase after HSCT. ► Airway distensibility with lung inflation increased and was correlated with lung density.
ISSN:1569-9048
1878-1519
DOI:10.1016/j.resp.2012.07.021