Morphological changes in peripapillary nerve fiber In multiple sclerosis patients

Purpose The aim of this study was to estimate the incidence of lesions in the peripapillary retinal nerve fiber layer in population of patients suffering from sclerosis multiplex Methods Material of this study consists of 57 subjects (114 eyes) suffering from multiple sclerosis, in observation in ou...

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Bibliographic Details
Published in:Acta ophthalmologica (Oxford, England) England), 2011-09, Vol.89 (s248), p.0-0
Main Authors: JANKOWSKA‐LECH, I, GRABSKA‐ LIBEREK, I, WASYLUK, J, TERELAK‐BORYS, B, PALASIK, W
Format: Article
Language:English
Subjects:
Classification
Data processing
Eye
Fibers
Glaucoma
Multiple sclerosis
Optic nerve
Retina
Sclerosis
Tomography
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Summary:Purpose The aim of this study was to estimate the incidence of lesions in the peripapillary retinal nerve fiber layer in population of patients suffering from sclerosis multiplex Methods Material of this study consists of 57 subjects (114 eyes) suffering from multiple sclerosis, in observation in our Department of Ophthalmology. In all patients spectral optical coherence tomography of the peripapillary retinal nerve fiber layer was performed by 3D‐ OCT 1000 (Topcon), glaucoma module, circular around the optical nerve head. Obtained data was analyzed, taking into consideration thickness of the nerve fiber layer in four sectors around the optic nerve head (ONH) and normative database classification (normal, borderline, outside normal limits). Outcomes were classified as borderline or outside normal limits when at least one eye was borderline or outside normal limits. Results In the obtained OCT results the following data was collected: normal group: 36 (63.2%), borderline group: 15 (26.3%) and outside normal group: 6 (10.5%). The particular numerical data of nerve fiber layer thickness in specific groups will be presented. Conclusion The percentage of patients with borderline or outside normal results of the nerve fiber layer thickness in the study group was significantly higher than in healthy population, e.g. in persons without glaucoma or sclerosis multiplex. This may suggest the common pathogenetical background of both diseases.
ISSN:1755-375X
1755-3768
DOI:10.1111/j.1755-3768.2011.316.x