Changes in Aortic Pulse Wave Velocity of Patients Undergoing Endovascular Repair of Abdominal Aortic Aneurysms

Purpose To assess changes in pulse wave velocity (PWV), a valid index of arterial stiffness, in patients undergoing endovascular repair (EVAR) of abdominal aortic aneurysm (AAA). Arterial stiffness is an independent marker of all-cause mortality and cardiovascular morbidity and mortality. Methods Fo...

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Bibliographic Details
Published in:Journal of endovascular therapy 2012-10, Vol.19 (5), p.661-666
Main Authors: Kadoglou, Nikolaos P.E., Moulakakis, Konstantinos G., Papadakis, Ioannis, Ikonomidis, Ignatios, Alepaki, Maria, Lekakis, John, Liapis, Christos D.
Format: Article
Language:English
Subjects:
Abdomen
Aged
Aneurysms
Aorta, Abdominal - physiopathology
Aorta, Abdominal - surgery
Aortic Aneurysm, Abdominal - diagnosis
Aortic Aneurysm, Abdominal - physiopathology
Aortic Aneurysm, Abdominal - surgery
Blood Vessel Prosthesis
Blood Vessel Prosthesis Implantation - instrumentation
Cardiovascular disease
Case-Control Studies
Chi-Square Distribution
Compliance
Endovascular Procedures - instrumentation
Family medical history
Heart rate
Hospitals
Humans
Male
Medical imaging
Middle Aged
Mortality
Multivariate Analysis
Predictive Value of Tests
Prospective Studies
Pulsatile Flow
Pulse Wave Analysis
Risk Factors
Stents
Studies
Surgery
Time Factors
Treatment Outcome
Variables
Vascular Stiffness
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Summary:Purpose To assess changes in pulse wave velocity (PWV), a valid index of arterial stiffness, in patients undergoing endovascular repair (EVAR) of abdominal aortic aneurysm (AAA). Arterial stiffness is an independent marker of all-cause mortality and cardiovascular morbidity and mortality. Methods Forty-eight consecutive male patients (mean age 71 ± 4 years) underwent elective EVAR (AAA group) after exclusion of patients with Marfan syndrome or other collagen-related disorders. Thirty-one age-matched men (mean age 69 ± 5 years) without overt cardiovascular disease served as controls. PWV and clinical parameters were determined at baseline in both groups and after 6 months in the AAA group. Results At baseline, the groups did not differ in demographic characteristics, lipid profile, or blood pressure levels (p>0.05). PWV was considerably higher in AAA than controls (p
ISSN:1526-6028
1545-1550
DOI:10.1583/JEVT-12-3916MR.1