Long-term reproductive outcome after hysteroscopic proximal tubal cannulation - an outcome analysis

• Published in: Australian & New Zealand journal of obstetrics & gynaecology 2012-10, Vol.52 (5), p.470-475
• Main Authors: Chung, Jacqueline P.W., Haines, Christopher J., Kong, Grace W.S.
• Format: Article
• Language: English
• Subjects: Adult; Catheterization - adverse effects; Chi-Square Distribution; Fallopian Tube Diseases - complications; Fallopian Tube Diseases - therapy; Fallopian Tube Patency Tests; Female; Humans; hysteroscopic proximal tubal cannulation; Hysteroscopy - adverse effects; Infertility, Female - etiology; Infertility, Female - therapy; laparoscopic chromopertubation; Laparoscopy - adverse effects; Logistic Models; Pregnancy; Pregnancy Rate; proximal tubal obstruction; reproductive outcome; Retrospective Studies; Time Factors; tubal infertility
• ISSN: 0004-8666; 1479-828X
• DOI: 10.1111/j.1479-828X.2012.01479.x

Background The optimal therapeutic method for proximal tubal obstruction (PTO) has yet to be defined. In addition, the reported successful recanalisation rate and reproductive outcome from hysteroscopic proximal tubal cannulation have been inconsistent. Aims To examine the morbidity and efficacy of laparoscopic–hysteroscopic proximal tubal cannulation for treating PTO. Material and Methods This was a retrospective study evaluating 70 infertile women with PTO who underwent laparoscopic–hysteroscopic proximal tubal cannulation in The Prince of Wales Hospital, a university‐affiliated hospital, from January 2005 to December 2010. Demographical data and operative details were reviewed. Women were then contacted by phone and completed a structured questionnaire. Recanalisation rate, intra‐operative complication, pregnancy rates and pregnancy outcomes were examined. Results Fifty women had successful proximal cannulation on at least one side of the tube, providing an overall successful recanalisation rate of 71.4% per woman and 67.0% per tube. The overall pregnancy rate after successful hysteroscopic proximal cannulation of at least one tube is 55%. The overall mean time to become pregnant from natural conception or via clomiphene induction after successful unilateral or bilateral hysteroscopic cannulation was 10.5 ± 8.9 months. The procedure is associated with minimal morbidity. No prognostic factors were significantly associated with recanalisation and pregnancy rate. Conclusion Laparoscopic–hysteroscopic cannulation for proximal obstruction is a procedure with minimal morbidity and a reasonable successful recanalisation rate. It should be considered as an alternative to in vitro fertilisation.