Determinants of Prognostically Relevant Intracoronary Electrocardiogram ST-Segment Shift During Coronary Balloon Occlusion

The prognostic relevance of quantitative an intracoronary occlusive electrocardiographic (ECG) ST-segment shift and its determinants have not been investigated in humans. In 765 patients with chronic stable coronary artery disease, the following simultaneous quantitative measurements were obtained d...

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Bibliographic Details
Published in:The American journal of cardiology 2012-11, Vol.110 (9), p.1234-1239
Main Authors: de Marchi, Stefano Fausto, MD, Streuli, Sabina, BS, Haefeli, Pascal, BS, Gloekler, Steffen, MD, Traupe, Tobias, MD, Warncke, Cornelius, MD, Rimoldi, Stefano F., MD, Stortecky, Stefan, MD, Steck, Hélène, RN, Seiler, Christian, MD
Format: Article
Language:English
Subjects:
Aged
Angioplasty, Balloon, Coronary - methods
Angioplasty, Balloon, Coronary - mortality
Balloon Occlusion - methods
Balloon Occlusion - mortality
Biological and medical sciences
Cardiology. Vascular system
Cardiovascular
Cardiovascular disease
Cohort Studies
Coronary Disease - diagnosis
Coronary Disease - mortality
Coronary Disease - therapy
Coronary heart disease
Coronary Occlusion - mortality
Coronary Occlusion - physiopathology
Coronary vessels
Electrocardiography
Electrocardiography - methods
Female
Heart
Heart attacks
Humans
Male
Medical sciences
Middle Aged
Mortality
Multivariate Analysis
Predictive Value of Tests
Prognosis
Regression Analysis
Risk Assessment
Sensitivity and Specificity
Survival Analysis
Time Factors
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Description
Summary:The prognostic relevance of quantitative an intracoronary occlusive electrocardiographic (ECG) ST-segment shift and its determinants have not been investigated in humans. In 765 patients with chronic stable coronary artery disease, the following simultaneous quantitative measurements were obtained during a 1-minute coronary balloon occlusion: intracoronary ECG ST-segment shift (recorded by angioplasty guidewire), mean aortic pressure, mean distal coronary pressure, and mean central venous pressure (CVP). Collateral flow index (CFI) was calculated as follows: (mean distal coronary pressure minus CVP)/(mean aortic pressure minus CVP). During an average follow-up duration of 50 ± 34 months, the cumulative mortality rate from all causes was significantly lower in the group with an ST-segment shift
ISSN:0002-9149
1879-1913
DOI:10.1016/j.amjcard.2012.06.023