Aza-oxindole synthesis via base promoted Truce-Smiles rearrangement

A novel efficient NaOtBu-mediated protocol for the synthesis of 3,3-disubstituted aza-oxindoles proceeds via a Truce-Smiles rearrangement-cyclisation pathway.

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Bibliographic Details
Published in:Chemical communications (Cambridge, England) England), 2012-11, Vol.48 (89), p.10957-10959
Main Authors: Dey, Chandan, Katayev, Dmitry, Ylijoki, Kai E O, Kündig, E Peter
Format: Article
Language:English
Subjects:
Aza Compounds - chemical synthesis
Cyclization
Indoles - chemical synthesis
Molecular Structure
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Description
Summary:A novel efficient NaOtBu-mediated protocol for the synthesis of 3,3-disubstituted aza-oxindoles proceeds via a Truce-Smiles rearrangement-cyclisation pathway.
ISSN:1359-7345
1364-548X
DOI:10.1039/c2cc36068c