Foetal and neonatal outcomes in women reporting ingestion of low or very low alcohol intake during pregnancy

Objective: This study aimed to assess the pregnancy outcomes of women who reported social intake of low or very low alcohol levels during pregnancy. Methods: Obstetric and foetal outcomes were assessed in a prospective cohort of 1667 pregnant women who reported low or very low alcohol consumption du...

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Published in:The journal of maternal-fetal & neonatal medicine 2012-11, Vol.25 (11), p.2186-2189
Main Authors: Han, Jung-Yeol, Choi, June-Seek, Ahn, Hyun-Kyoung, Kim, Min-Hyoung, Chung, Jin-Hoon, Ryu, Hyun-Mee, Kim, Moon-Young, Yang, Jae-Hyug, Nava-Ocampo, Alejandro A.
Format: Article
Language:English
Subjects:
Adult
Alcohol consumption
Alcohol Drinking - adverse effects
Alcohol Drinking - epidemiology
Case-Control Studies
Cohort Studies
Drug-Related Side Effects and Adverse Reactions
Eating - physiology
Ethanol - administration & dosage
Ethanol - pharmacology
Female
Fetus - drug effects
Fetus - physiology
Gestational Age
Humans
Infant, Newborn - physiology
Maternal Exposure - statistics & numerical data
Pregnancy
Pregnancy Outcome - epidemiology
Prenatal Exposure Delayed Effects - epidemiology
Prenatal Exposure Delayed Effects - etiology
teratogens
transplancental exposure
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Summary:Objective: This study aimed to assess the pregnancy outcomes of women who reported social intake of low or very low alcohol levels during pregnancy. Methods: Obstetric and foetal outcomes were assessed in a prospective cohort of 1667 pregnant women who reported low or very low alcohol consumption during pregnancy (cases) and 1840 alcohol-abstainer women (controls). Results: Among cases, alcohol consumption occurred during the first 4.4 (median) weeks of pregnancy, with a median ingestion of 1.0 (0.01-6.0) drinks/week, equivalent to 7.6 (0.09-47.5) g/week. Cigarette smoking was reported approximately four times more often in the exposed group than in the controls (p < 0.001). Pregnancy outcomes were similar between groups. There were 37 (2.4%) babies born with malformations in the exposed group and 41 (2.4%) in the control group (p = 0.9). Conclusions: Low-to-very low levels of alcohol ingestion during pregnancy do not appear to be associated with adverse maternal or foetal outcomes.
ISSN:1476-7058
1476-4954
DOI:10.3109/14767058.2012.684107