Effects of food restriction imposed to adult rats on the bone growth and the histological structure of the thyroid in their youth

Our objective was the study of the development and the maturation of pups whose mothers were subjected to intermittent fasting. Eight pregnant female Wistar rats were distributed into two groups of four adult females. The rats of the first group were subjected to intermittent fasting beginning on th...

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Bibliographic Details
Published in:Pathologie biologie (Paris) 2012-10, Vol.60 (5), p.296-300
Main Authors: Kamel, M, Barkia, A, Nasri, M, Rebaï, T, Sahnoun, Z, Kassis, M, Aouidet, A
Format: Article
Language:fre
Subjects:
Age Factors
Animals
Body Weight - physiology
Bone Density
Bone Development - physiology
Caloric Restriction - adverse effects
Cell Count
Female
Food Deprivation - physiology
Organ Size - physiology
Pregnancy
Prenatal Exposure Delayed Effects - etiology
Prenatal Exposure Delayed Effects - pathology
Prenatal Exposure Delayed Effects - physiopathology
Prenatal Nutritional Physiological Phenomena
Rats
Rats, Wistar
Thyroid Gland - blood supply
Thyroid Gland - pathology
Thyroid Gland - ultrastructure
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Summary:Our objective was the study of the development and the maturation of pups whose mothers were subjected to intermittent fasting. Eight pregnant female Wistar rats were distributed into two groups of four adult females. The rats of the first group were subjected to intermittent fasting beginning on the 14th day of gestation and continued 21 days after parturition. The rats of the second group were normally fed. The young of both groups of rats were sacrificed at the age of 21 days. The pups of the female rats submitted to food restriction showed a reduction of the body weight (-35%), of the thyroid iodine content (P
ISSN:1768-3114
DOI:10.1016/j.patbio.2011.08.001