Serum CRP Protein as a Differential Marker in Cancer

The objective of this study was to measure the serum concentrations of C-reactive protein (CRP) in cancer patients and compare with those of immune disease patients and healthy individuals for discriminatory analysis. For this purpose, automatic systems for special protein analysis (Type: Drcon Diog...

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Bibliographic Details
Published in:Cell biochemistry and biophysics 2012-11, Vol.64 (2), p.89-93
Main Authors: Juan, Hu, Qijun, Wang, Junlan, Liu
Format: Article
Language:English
Subjects:
Adult
Aged
Autoimmune Diseases - blood
Autoimmune Diseases - diagnosis
Automation, Laboratory
Biochemistry
Biological and Medical Physics
Biomarkers, Tumor - blood
Biomedical and Life Sciences
Biophysics
Biotechnology
C-Reactive Protein - analysis
Case-Control Studies
Cell Biology
Diagnosis, Differential
Female
Humans
Inflammation - blood
Inflammation - diagnosis
Life Sciences
Male
Middle Aged
Neoplasms - blood
Neoplasms - diagnosis
Original Paper
Pharmacology/Toxicology
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Summary:The objective of this study was to measure the serum concentrations of C-reactive protein (CRP) in cancer patients and compare with those of immune disease patients and healthy individuals for discriminatory analysis. For this purpose, automatic systems for special protein analysis (Type: Drcon Diognostica Tarbox) was used to measure serum CRP concentrations in 276 cancer patients (Group A), 110 immune disease patients (Group B), 161 phlogistic patients (Group C), and 125 age-matched healthy individuals (Group D). Our data show that serum CRP concentrations in Group A were significantly higher than those in Groups B and D, whereas CRP concentrations in Group B were higher than those in Group D. The differences of serum CRP concentrations between Groups A and B as well as between Groups B and D were significant ( P  
ISSN:1085-9195
1559-0283
DOI:10.1007/s12013-012-9375-9