The role of sleep problems and circadian clock genes in childhood psychiatric disorders

CLOCK gene research and the analysis of circadian rhythmicity on the behavioural, cellular and molecular level are increasingly contributing to accumulate clinically relevant knowledge in the fields of neuroscience, psychopharmacology and adult psychiatry. However, the role of circadian phenomena, i...

Full description

Saved in:
Bibliographic Details
Published in:Journal of Neural Transmission 2012-10, Vol.119 (10), p.1097-1104
Main Authors: Dueck, Alexander, Thome, Johannes, Haessler, Frank
Format: Article
Language:English
Subjects:
Adolescence
Adolescent
Animals
Anxiety
Attention deficit hyperactivity disorder
Biological Child and Adolescent Psychiatry - Review article
Child
Children
Circadian Rhythm - genetics
Circadian rhythms
CLOCK protein
CLOCK Proteins - genetics
Humans
Medicine
Medicine & Public Health
Mental disorders
Mental Disorders - complications
Mental Disorders - genetics
Mood
Nervous system
Neurology
Neurosciences
Psychiatry
Schizophrenia
Sleep
Sleep disorders
Sleep Wake Disorders - etiology
Sleep Wake Disorders - genetics
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:CLOCK gene research and the analysis of circadian rhythmicity on the behavioural, cellular and molecular level are increasingly contributing to accumulate clinically relevant knowledge in the fields of neuroscience, psychopharmacology and adult psychiatry. However, the role of circadian phenomena, including sleep alterations in mental disorders during childhood and adolescence remains largely enigmatic. Fortunately, recent publications have addressed this problem and there is now some evidence available highlighting the relevance of CLOCK genes in conditions, such as ADHD, mood disorders, schizophrenia and anxiety disorders.
ISSN:0300-9564
1435-1463
DOI:10.1007/s00702-012-0834-7