Developmental expression and subcellular distribution of synaptotagmin 11 in rat hippocampus

• Published in: Neuroscience 2012-12, Vol.225, p.35-43
• Main Authors: Yeo, H, Kim, H.-w, Mo, J, Lee, D, Han, S, Hong, S, Koh, M.J, Sun, W, Choi, S, Rhyu, I.J, Kim, H, Lee, H.W
• Format: Article
• Language: English
• Subjects: Age Factors; Animals; Animals, Newborn; Biological and medical sciences; Brain - growth & development; Brain - metabolism; Brain - ultrastructure; Carrier Proteins - metabolism; Cell Membrane - metabolism; Cells, Cultured; Coculture Techniques; Development. Senescence. Regeneration. Transplantation; Disks Large Homolog 4 Protein; Embryo, Mammalian; Fundamental and applied biological sciences. Psychology; Gene Expression Regulation, Developmental - physiology; Glucose Transporter Type 1 - metabolism; Green Fluorescent Proteins - genetics; hippocampus; Hippocampus - cytology; Humans; Intracellular Signaling Peptides and Proteins - metabolism; Intracellular Space - metabolism; Membrane Proteins - metabolism; Microscopy, Electron, Transmission; Nerve Tissue Proteins - metabolism; Neurology; Neurons - metabolism; Neurons - ultrastructure; postsynapse; presynapse; Rats; RNA, Messenger - metabolism; Synapses - metabolism; Synapses - ultrastructure; synaptic vesicle; synaptotagmin 11; Synaptotagmins - genetics; Synaptotagmins - metabolism; Transfection; Vertebrates: nervous system and sense organs; Vesicular Inhibitory Amino Acid Transport Proteins - metabolism
• ISSN: 0306-4522; 1873-7544
• DOI: 10.1016/j.neuroscience.2012.08.062

Graphical abstract Highlights ► Syt11 is expressed in the central nervous system. ► Syt11 is a pre and postsynaptic molecule in rat hippocampal neurons. ► Exogenous Syt11 may homo-multimerize in HEK293T cells.