Risk factors associated with linezolid-nonsusceptible enterococcal infections

Linezolid is one of few treatment options available for vancomycin-resistant enterococci. The present study investigated risk factors for linezolid-nonsusceptible enterococci using a case-control study of 15 cases and 60 control patients. Previous hospitalization, admission to a medical service, com...

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Bibliographic Details
Published in:American journal of infection control 2012-11, Vol.40 (9), p.886-887
Main Authors: McGregor, Jessina C., PhD, Hartung, Daniel M., PharmD, MPH, Allen, George P., PharmD, Taplitz, Randy A., MD, Traver, Robin, PharmD, Tong, Tony, PharmD, Bearden, David T., PharmD
Format: Article
Language:English
Subjects:
Acetamides - pharmacology
Anti-Bacterial Agents - pharmacology
Antibacterial agents
Antibiotic resistance
Antibiotics. Antiinfectious agents. Antiparasitic agents
Biological and medical sciences
Case-Control Studies
Drug resistance
Drug Resistance, Bacterial
Enterococcus
Enterococcus - drug effects
Enterococcus - isolation & purification
Epidemiology
Epidemiology. Vaccinations
Female
General aspects
Gram-positive bacteria
Gram-Positive Bacterial Infections - epidemiology
Gram-Positive Bacterial Infections - microbiology
Humans
Infection Control
Infectious Disease
Infectious diseases
Linezolid
Male
Medical sciences
Middle Aged
Nosocomial infections
Oxazolidinones - pharmacology
Pharmacology. Drug treatments
Risk Factors
Vancomycin resistance
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Summary:Linezolid is one of few treatment options available for vancomycin-resistant enterococci. The present study investigated risk factors for linezolid-nonsusceptible enterococci using a case-control study of 15 cases and 60 control patients. Previous hospitalization, admission to a medical service, comorbidity, and linezolid and sulfonamide therapy were identified as risk factors.
ISSN:0196-6553
1527-3296
DOI:10.1016/j.ajic.2011.11.005