Platelet Count and Mean Platelet Volume in Patients With In-Hospital Deep Venous Thrombosis

• Published in: Clinical and applied thrombosis/hemostasis 2012-11, Vol.18 (6), p.650-653
• Main Authors: Çil, Habib, Yavuz, Celal, İslamoğlu, Yahya, Tekbaş, Ebru Öntürk, Demirtaş, Sinan, Atılgan, Zuhal Arıtürk, Gündüz, Ercan, Benli, Emre Demir, Tanrıverdi, Halis
• Format: Article
• Language: English
• Subjects: Adult; Aged; Aged, 80 and over; Biomarkers - blood; Blood Platelets; Body mass index; Female; Hospitalization; Humans; Male; Middle Aged; Platelet Count; Retrospective Studies; Risk factors; Thrombosis; Venous Thrombosis - blood
• ISSN: 1076-0296; 1938-2723
• DOI: 10.1177/1076029611435838

Aim: To investigate the relationship between mean platelet volume (MPV) and in-hospital deep venous thrombosis (DVT). Material and methods: 147 patients with the diagnosis of DVT and 149 control participants were included in the study. For all participants, clinical risk factors, smoking status, and other demographic data were recorded from hospital registries. The data of patients with DVT were compared with the control participants. Results: Mean MPV was significantly higher in patients with DVT than the control group (8.91 ± 1.86 vs 7.86 ± 0.9; P < .001). Body mass index, smoking frequency, hematocrit, and platelet count were significantly correlated with MPV. Independent predictors of in-hospital DVT were MPV (odds ratio [OR] = 1.5; 95% confidence interval [CI] = 1.2-1.87; P ≤ .001), body mass index (OR = 1.17; 95% CI = 1.04-1.34; P = .012), and smoking (OR = 1.83; 95% CI = 1.09-3.08; P = .023). Conclusion: Mean platelet volume was significantly higher in patients with DVT, and it is an independent predictor of in-hospital DVT.